The University of Southampton
University of Southampton Institutional Repository
Warning ePrints Soton is experiencing an issue with some file downloads not being available. We are working hard to fix this. Please bear with us.

Increasing the uptake of prevention of mother-to-child transmission of HIV services in a resource-limited setting

Increasing the uptake of prevention of mother-to-child transmission of HIV services in a resource-limited setting
Increasing the uptake of prevention of mother-to-child transmission of HIV services in a resource-limited setting
BACKGROUND: As in other resource limited settings, the Ministry of Health in Zambia is challenged to make affordable and acceptable PMTCT interventions accessible and available. With a 14.3% HIV prevalence, the MOH estimates over one million people are HIV positive in Zambia. Approximately 500,000 children are born annually in Zambia and 40,000 acquire the infection vertically each year if no intervention is offered. This study sought to review uptake of prevention of mother-to-child (PMTCT) services in a resource-limited setting following the introduction of context-specific interventions.

METHODS: Interventions to improve PMTCT uptake were introduced into 38 sites providing PMTCT services in Zambia in July 2005. Baseline and follow up service data were collected on a monthly basis through September 2008. Data was checked for internal and external consistency using logic built into databases used for data management. Data audits were conducted to determine accuracy and reliability. Trends were analyzed pre- and post- intervention.

RESULTS: Uptake among pregnant women increased across the 13 quarters (39 months) of observation, particularly in the case of acceptance of counseling and HIV testing from 45% to 90% (p value = 0.00) in the first year and 99% by year 3 (p value = 0.00). Receipt of complete course of antiretroviral (ARV) prophylaxis increased from 29% to 66% (p = 0.00) in the first year and 97% by year 3 (p value = 0.00). There was also significant improvement in the percentage of HIV positive pregnant women referred for clinical care.

CONCLUSIONS: Uptake of PMTCT services in resource-limited settings can be improved by utilizing innovative alternatives to mitigate the effects of human resource shortage such as by providing technical assistance and mentorship beyond regular training courses, integrating PMTCT services into existing maternal and child health structures, addressing information gaps, mobilizing traditional and opinion leaders and building strong relationships with the government. These health system based approaches provide a sustainable improvement in the capacity and uptake of services.
1472-6963
29-[10pp]
Torpey, Kwasi
815aebdc-b12c-4c50-b772-4e1923fd61c0
Kabaso, Mushota
180b4c6b-f956-4d1e-a371-ea03917ad42a
Kasonde, Prisca
9296067c-a81d-4991-b8da-e4800136f3ed
Dirks, Rebecca
1d8217e0-8325-4481-ba02-dc7e444d925b
Bweupe, Maximillian
d181c40c-4e11-4acb-b0b0-601921eeb19d
Thompson, Catherine
f0fa011e-fd46-4ced-a126-08d27eef46f5
Mukadi, Ya Diul
004ae3eb-32ff-4f3e-98a1-9e3deb5a1cdb
Torpey, Kwasi
815aebdc-b12c-4c50-b772-4e1923fd61c0
Kabaso, Mushota
180b4c6b-f956-4d1e-a371-ea03917ad42a
Kasonde, Prisca
9296067c-a81d-4991-b8da-e4800136f3ed
Dirks, Rebecca
1d8217e0-8325-4481-ba02-dc7e444d925b
Bweupe, Maximillian
d181c40c-4e11-4acb-b0b0-601921eeb19d
Thompson, Catherine
f0fa011e-fd46-4ced-a126-08d27eef46f5
Mukadi, Ya Diul
004ae3eb-32ff-4f3e-98a1-9e3deb5a1cdb

Torpey, Kwasi, Kabaso, Mushota, Kasonde, Prisca, Dirks, Rebecca, Bweupe, Maximillian, Thompson, Catherine and Mukadi, Ya Diul (2010) Increasing the uptake of prevention of mother-to-child transmission of HIV services in a resource-limited setting. BMC Health Services Research, 10 (1), 29-[10pp]. (doi:10.1186/1472-6963-10-29). (PMID:20109210)

Record type: Article

Abstract

BACKGROUND: As in other resource limited settings, the Ministry of Health in Zambia is challenged to make affordable and acceptable PMTCT interventions accessible and available. With a 14.3% HIV prevalence, the MOH estimates over one million people are HIV positive in Zambia. Approximately 500,000 children are born annually in Zambia and 40,000 acquire the infection vertically each year if no intervention is offered. This study sought to review uptake of prevention of mother-to-child (PMTCT) services in a resource-limited setting following the introduction of context-specific interventions.

METHODS: Interventions to improve PMTCT uptake were introduced into 38 sites providing PMTCT services in Zambia in July 2005. Baseline and follow up service data were collected on a monthly basis through September 2008. Data was checked for internal and external consistency using logic built into databases used for data management. Data audits were conducted to determine accuracy and reliability. Trends were analyzed pre- and post- intervention.

RESULTS: Uptake among pregnant women increased across the 13 quarters (39 months) of observation, particularly in the case of acceptance of counseling and HIV testing from 45% to 90% (p value = 0.00) in the first year and 99% by year 3 (p value = 0.00). Receipt of complete course of antiretroviral (ARV) prophylaxis increased from 29% to 66% (p = 0.00) in the first year and 97% by year 3 (p value = 0.00). There was also significant improvement in the percentage of HIV positive pregnant women referred for clinical care.

CONCLUSIONS: Uptake of PMTCT services in resource-limited settings can be improved by utilizing innovative alternatives to mitigate the effects of human resource shortage such as by providing technical assistance and mentorship beyond regular training courses, integrating PMTCT services into existing maternal and child health structures, addressing information gaps, mobilizing traditional and opinion leaders and building strong relationships with the government. These health system based approaches provide a sustainable improvement in the capacity and uptake of services.

This record has no associated files available for download.

More information

Published date: 28 January 2010
Organisations: Mathematical Sciences

Identifiers

Local EPrints ID: 353686
URI: http://eprints.soton.ac.uk/id/eprint/353686
ISSN: 1472-6963
PURE UUID: 27b9d56d-7391-4b9b-b100-ca7d58df2104

Catalogue record

Date deposited: 13 Jun 2013 15:23
Last modified: 08 Jan 2022 15:05

Export record

Altmetrics

Contributors

Author: Kwasi Torpey
Author: Mushota Kabaso
Author: Prisca Kasonde
Author: Rebecca Dirks
Author: Maximillian Bweupe
Author: Catherine Thompson
Author: Ya Diul Mukadi

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×