Patient-reported outcomes of cancer survivors in England 1-5 years after diagnosis: a cross-sectional survey
Patient-reported outcomes of cancer survivors in England 1-5 years after diagnosis: a cross-sectional survey
OBJECTIVES: To determine the feasibility of collecting population-based patient-reported outcome measures (PROMs) in assessing quality of life (QoL) to inform the development of a national PROMs programme for cancer and to begin to describe outcomes in a UK cohort of survivors.
DESIGN: Cross-sectional postal survey of cancer survivors using a population-based sampling approach.
SETTING: English National Health Service.
PARTICIPANTS: 4992 breast, colorectal, prostate and non-Hodgkin's lymphoma (NHL) survivors 1-5 years from diagnosis.
PRIMARY AND SECONDARY OUTCOME MEASURES: Implementation issues, response rates, cancer-specific morbidities utilising items including the EQ5D, tumour-specific subscales of the Functional Assessment of Cancer Therapy and Social Difficulties Inventory.
RESULTS: 3300 (66%) survivors returned completed questionnaires. The majority aged 85+ years did not respond and the response rates were lower for those from more deprived area. Response rates did not differ by gender, time since diagnosis or cancer type. The presence of one or more long-term conditions was associated with significantly lower QoL scores. Individuals from most deprived areas reported lower QoL scores and poorer outcomes on other measures, as did those self-reporting recurrent disease or uncertainty about disease status. QoL scores were comparable at all time points for all cancers except NHL. QoL scores were lower than those from the general population in Health Survey for England (2008) and General Practice Patient Survey (2012). 47% of patients reported fear of recurrence, while 20% reported moderate or severe difficulties with mobility or usual activities. Bowel and urinary problems were common among colorectal and prostate patients. Poor bowel and bladder control were significantly associated with lower QoL.
CONCLUSIONS: This method of assessing QoL of cancer survivors is feasible and acceptable to most survivors. Routine collection of national population-based PROMs will enable the identification of, and the support for, the specific needs of survivors while allowing for comparison of outcome by service provider.
e002317-[13pp]
Glaser, A.W.
0e61ed22-7b15-43e1-af67-8840fbb09879
Fraser, L.K.
b7d56bc3-79e0-4fe6-848c-7d6cddfcd40c
Corner, J.
eddc9d69-aa12-4de5-8ab0-b20a6b5765fa
Feltbower, R.
efada5d7-ce80-425b-b864-3adff22b58ed
Morris, E.J.
4d75466a-7b10-48a9-855c-3da95c097d30
Hartwell, G.
0c6aad3e-b71b-49e1-9af0-19d6a0f72162
Richards, M.
d76b0506-723e-4ed8-9fbc-a522f515e797
10 April 2013
Glaser, A.W.
0e61ed22-7b15-43e1-af67-8840fbb09879
Fraser, L.K.
b7d56bc3-79e0-4fe6-848c-7d6cddfcd40c
Corner, J.
eddc9d69-aa12-4de5-8ab0-b20a6b5765fa
Feltbower, R.
efada5d7-ce80-425b-b864-3adff22b58ed
Morris, E.J.
4d75466a-7b10-48a9-855c-3da95c097d30
Hartwell, G.
0c6aad3e-b71b-49e1-9af0-19d6a0f72162
Richards, M.
d76b0506-723e-4ed8-9fbc-a522f515e797
Glaser, A.W., Fraser, L.K., Corner, J., Feltbower, R., Morris, E.J., Hartwell, G. and Richards, M.
(2013)
Patient-reported outcomes of cancer survivors in England 1-5 years after diagnosis: a cross-sectional survey.
British Medical Journal, 3 (4), .
(doi:10.1136/bmjopen-2012-002317).
(PMID:23578682)
Abstract
OBJECTIVES: To determine the feasibility of collecting population-based patient-reported outcome measures (PROMs) in assessing quality of life (QoL) to inform the development of a national PROMs programme for cancer and to begin to describe outcomes in a UK cohort of survivors.
DESIGN: Cross-sectional postal survey of cancer survivors using a population-based sampling approach.
SETTING: English National Health Service.
PARTICIPANTS: 4992 breast, colorectal, prostate and non-Hodgkin's lymphoma (NHL) survivors 1-5 years from diagnosis.
PRIMARY AND SECONDARY OUTCOME MEASURES: Implementation issues, response rates, cancer-specific morbidities utilising items including the EQ5D, tumour-specific subscales of the Functional Assessment of Cancer Therapy and Social Difficulties Inventory.
RESULTS: 3300 (66%) survivors returned completed questionnaires. The majority aged 85+ years did not respond and the response rates were lower for those from more deprived area. Response rates did not differ by gender, time since diagnosis or cancer type. The presence of one or more long-term conditions was associated with significantly lower QoL scores. Individuals from most deprived areas reported lower QoL scores and poorer outcomes on other measures, as did those self-reporting recurrent disease or uncertainty about disease status. QoL scores were comparable at all time points for all cancers except NHL. QoL scores were lower than those from the general population in Health Survey for England (2008) and General Practice Patient Survey (2012). 47% of patients reported fear of recurrence, while 20% reported moderate or severe difficulties with mobility or usual activities. Bowel and urinary problems were common among colorectal and prostate patients. Poor bowel and bladder control were significantly associated with lower QoL.
CONCLUSIONS: This method of assessing QoL of cancer survivors is feasible and acceptable to most survivors. Routine collection of national population-based PROMs will enable the identification of, and the support for, the specific needs of survivors while allowing for comparison of outcome by service provider.
This record has no associated files available for download.
More information
Published date: 10 April 2013
Organisations:
Faculty of Health Sciences
Identifiers
Local EPrints ID: 354113
URI: http://eprints.soton.ac.uk/id/eprint/354113
ISSN: 0959-8138
PURE UUID: 8e0205b5-da56-4c48-8a7a-f9aee39455a6
Catalogue record
Date deposited: 03 Jul 2013 14:31
Last modified: 14 Mar 2024 14:13
Export record
Altmetrics
Contributors
Author:
A.W. Glaser
Author:
L.K. Fraser
Author:
J. Corner
Author:
R. Feltbower
Author:
E.J. Morris
Author:
G. Hartwell
Author:
M. Richards
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics