The University of Southampton
University of Southampton Institutional Repository

Maternal height and child growth patterns

Maternal height and child growth patterns
Maternal height and child growth patterns
Objective: to examine associations between maternal height and child growth during 4 developmental periods: intrauterine, birth to age 2 years, age 2 years to mid-childhood (MC), and MC to adulthood.

Study design: pooled analysis of maternal height and offspring growth using 7630 mother–child pairs from 5 birth cohorts (Brazil, Guatemala, India, the Philippines, and South Africa). We used conditional height measures that control for collinearity in height across periods. We estimated associations between maternal height and offspring growth using multivariate regression models adjusted for household income, child sex, birth order, and study site.

Results: maternal height was associated with birth weight and with both height and conditional height at each age examined. The strongest associations with conditional heights were for adulthood and 2 years of age. A 1-cm increase in maternal height predicted a 0.024 (95% CI: 0.021-0.028) SD increase in offspring birth weight, a 0.037 (95% CI: 0.033-0.040) SD increase in conditional height at 2 years, a 0.025 (95% CI: 0.021-0.029 SD increase in conditional height in MC, and a 0.044 (95% CI: 0.040-0.048) SD increase in conditional height in adulthood. Short mothers (<150.1 cm) were more likely to have a child who was stunted at 2 years (prevalence ratio = 3.20 (95% CI: 2.80-3.60) and as an adult (prevalence ratio = 4.74, (95% CI: 4.13-5.44). There was no evidence of heterogeneity by site or sex.

Conclusion: maternal height influences offspring linear growth over the growing period. These influences likely include genetic and non-genetic factors, including nutrition-related intergenerational influences on growth that prevent the attainment of genetic height potential in low- and middle-income countries
0022-3476
Addo, O.Y.
df71a19b-884e-45d0-b6dc-fa9b641c1904
Stein, A.D.
9120fff8-4ef6-4c07-a69f-ebe55dcb1243
Fall, Caroline H.D.
7171a105-34f5-4131-89d7-1aa639893b18
Gigante, D.P.
08d63acc-872c-4231-8546-e35d2b7049f0
Guntupalli, Aravinda Meera
6ab00497-f86b-4bec-b393-c35a0c1054c9
Horta, B.L.
c1c0cf75-59af-47f3-8e02-20297f95bc1f
Kuzawa, C.W.
783f0645-d899-4a33-98ee-d964852e67ff
Lee, N.
78a65697-823f-4128-bfa2-cc9443403e07
Norris, S.A.
0f6066b6-036e-4606-8cd2-ae7a2fbdbd73
Prabhakaran, P.
0a38097e-6100-40df-b944-eb12fd854f27
Richter, L.M.
c76cf803-b586-4bc9-b82a-1dd6f16b65f4
Sachdev, H.S.
9c9c8153-4c13-4e32-a1e9-798872efe4cb
Martorell, R.
9ee73323-0528-4eff-93e3-c96fb1067356
Consortium on Health Orientated Research in Transitional Societies (COHORTS) Group
Addo, O.Y.
df71a19b-884e-45d0-b6dc-fa9b641c1904
Stein, A.D.
9120fff8-4ef6-4c07-a69f-ebe55dcb1243
Fall, Caroline H.D.
7171a105-34f5-4131-89d7-1aa639893b18
Gigante, D.P.
08d63acc-872c-4231-8546-e35d2b7049f0
Guntupalli, Aravinda Meera
6ab00497-f86b-4bec-b393-c35a0c1054c9
Horta, B.L.
c1c0cf75-59af-47f3-8e02-20297f95bc1f
Kuzawa, C.W.
783f0645-d899-4a33-98ee-d964852e67ff
Lee, N.
78a65697-823f-4128-bfa2-cc9443403e07
Norris, S.A.
0f6066b6-036e-4606-8cd2-ae7a2fbdbd73
Prabhakaran, P.
0a38097e-6100-40df-b944-eb12fd854f27
Richter, L.M.
c76cf803-b586-4bc9-b82a-1dd6f16b65f4
Sachdev, H.S.
9c9c8153-4c13-4e32-a1e9-798872efe4cb
Martorell, R.
9ee73323-0528-4eff-93e3-c96fb1067356

Addo, O.Y., Stein, A.D., Fall, Caroline H.D., Gigante, D.P., Guntupalli, Aravinda Meera, Horta, B.L., Kuzawa, C.W., Lee, N., Norris, S.A., Prabhakaran, P., Richter, L.M., Sachdev, H.S. and Martorell, R. , Consortium on Health Orientated Research in Transitional Societies (COHORTS) Group (2013) Maternal height and child growth patterns. Journal of Pediatrics. (doi:10.1016/j.jpeds.2013.02.002). (PMID:23477997)

Record type: Article

Abstract

Objective: to examine associations between maternal height and child growth during 4 developmental periods: intrauterine, birth to age 2 years, age 2 years to mid-childhood (MC), and MC to adulthood.

Study design: pooled analysis of maternal height and offspring growth using 7630 mother–child pairs from 5 birth cohorts (Brazil, Guatemala, India, the Philippines, and South Africa). We used conditional height measures that control for collinearity in height across periods. We estimated associations between maternal height and offspring growth using multivariate regression models adjusted for household income, child sex, birth order, and study site.

Results: maternal height was associated with birth weight and with both height and conditional height at each age examined. The strongest associations with conditional heights were for adulthood and 2 years of age. A 1-cm increase in maternal height predicted a 0.024 (95% CI: 0.021-0.028) SD increase in offspring birth weight, a 0.037 (95% CI: 0.033-0.040) SD increase in conditional height at 2 years, a 0.025 (95% CI: 0.021-0.029 SD increase in conditional height in MC, and a 0.044 (95% CI: 0.040-0.048) SD increase in conditional height in adulthood. Short mothers (<150.1 cm) were more likely to have a child who was stunted at 2 years (prevalence ratio = 3.20 (95% CI: 2.80-3.60) and as an adult (prevalence ratio = 4.74, (95% CI: 4.13-5.44). There was no evidence of heterogeneity by site or sex.

Conclusion: maternal height influences offspring linear growth over the growing period. These influences likely include genetic and non-genetic factors, including nutrition-related intergenerational influences on growth that prevent the attainment of genetic height potential in low- and middle-income countries

Full text not available from this repository.

More information

e-pub ahead of print date: 7 March 2013
Organisations: Faculty of Medicine, Social Sciences, Faculty of Humanities

Identifiers

Local EPrints ID: 354215
URI: http://eprints.soton.ac.uk/id/eprint/354215
ISSN: 0022-3476
PURE UUID: 2f09b8fb-ef73-498a-b7d8-8c6dbb4d49fd
ORCID for Caroline H.D. Fall: ORCID iD orcid.org/0000-0003-4402-5552

Catalogue record

Date deposited: 04 Jul 2013 09:00
Last modified: 18 Feb 2021 16:37

Export record

Altmetrics

Contributors

Author: O.Y. Addo
Author: A.D. Stein
Author: D.P. Gigante
Author: Aravinda Meera Guntupalli
Author: B.L. Horta
Author: C.W. Kuzawa
Author: N. Lee
Author: S.A. Norris
Author: P. Prabhakaran
Author: L.M. Richter
Author: H.S. Sachdev
Author: R. Martorell
Corporate Author: Consortium on Health Orientated Research in Transitional Societies (COHORTS) Group

University divisions

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×