Nonlinear pressure-flow relationships for passive microfluidic valves
Nonlinear pressure-flow relationships for passive microfluidic valves
An analytical solution is presented for the nonlinear pressure-flow relationship of deformable passive valves, which are formed by bonding a deformable film over etched channels separated by a weir. A fluidic pathway connecting the channels is opened when the upstream pressure creates a tunnel along a predefined narrow strip where the film is not bonded to the weir. When the width of the strip is comparable to the inlet channel width, the predicted closed-form pressure-flow rate relationship is in excellent agreement with experiments, which determine pressures by measuring film deflections for prescribed flow rates. The validated closed-form models involve no fitting parameters, and provide the foundation to design passive diodes with specific nonlinear pressure-flow characteristics.
2691-2697
Seker, Erkin
2583be7e-b2c4-4947-b91e-b5ffd5d4a4df
Leslie, Daniel C.
cfba1079-7234-4c99-a459-3501f1ce5df5
Haj-Hariri, Hossein
9f8f9523-a915-43f3-b935-a849d0428ec8
Landers, James P.
f85edaa2-5c24-4f2d-be3d-c84e631833ad
Utz, Marcel
c84ed64c-9e89-4051-af39-d401e423891b
Begley, Matthew R.
9f4e52bc-507a-4ef6-910f-bd11d25c2209
21 September 2009
Seker, Erkin
2583be7e-b2c4-4947-b91e-b5ffd5d4a4df
Leslie, Daniel C.
cfba1079-7234-4c99-a459-3501f1ce5df5
Haj-Hariri, Hossein
9f8f9523-a915-43f3-b935-a849d0428ec8
Landers, James P.
f85edaa2-5c24-4f2d-be3d-c84e631833ad
Utz, Marcel
c84ed64c-9e89-4051-af39-d401e423891b
Begley, Matthew R.
9f4e52bc-507a-4ef6-910f-bd11d25c2209
Seker, Erkin, Leslie, Daniel C., Haj-Hariri, Hossein, Landers, James P., Utz, Marcel and Begley, Matthew R.
(2009)
Nonlinear pressure-flow relationships for passive microfluidic valves.
Lab on a Chip, 9 (18), .
(doi:10.1039/B903960K).
(PMID:19704985)
Abstract
An analytical solution is presented for the nonlinear pressure-flow relationship of deformable passive valves, which are formed by bonding a deformable film over etched channels separated by a weir. A fluidic pathway connecting the channels is opened when the upstream pressure creates a tunnel along a predefined narrow strip where the film is not bonded to the weir. When the width of the strip is comparable to the inlet channel width, the predicted closed-form pressure-flow rate relationship is in excellent agreement with experiments, which determine pressures by measuring film deflections for prescribed flow rates. The validated closed-form models involve no fitting parameters, and provide the foundation to design passive diodes with specific nonlinear pressure-flow characteristics.
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e-pub ahead of print date: 24 June 2009
Published date: 21 September 2009
Organisations:
Magnetic Resonance
Identifiers
Local EPrints ID: 354822
URI: http://eprints.soton.ac.uk/id/eprint/354822
ISSN: 1473-0197
PURE UUID: 0a21433f-f629-499d-acae-1fcfed8984ff
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Date deposited: 23 Jul 2013 11:28
Last modified: 15 Mar 2024 03:44
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Contributors
Author:
Erkin Seker
Author:
Daniel C. Leslie
Author:
Hossein Haj-Hariri
Author:
James P. Landers
Author:
Matthew R. Begley
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