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The paradox of overnutrition in aging and cognition

The paradox of overnutrition in aging and cognition
The paradox of overnutrition in aging and cognition
Populations of many countries are becoming increasingly overweight and obese, driven largely by excessive calorie intake and reduced physical activity; greater body mass is accompanied by epidemic levels of comorbid metabolic diseases. At the same time, individuals are living longer. The combination of aging and the increased prevalence of metabolic disease is associated with increases in aging-related comorbid diseases such as Alzheimer's disease, cerebrovascular dementia, and sarcopenia. Here, correlative and causal links between diseases of overnutrition and diseases of aging and cognition are explored.

overnutrition, obesity, cognitive decline, Alzheimer’s disease, sarcopenia
0077-8923
31-43
Fielding, Roger A.
36b26592-ce59-4443-ab26-185919da78c0
Gunstad, John
3616be66-fb84-4505-a649-5dfb4ba2af88
Gustafson, Deborah R.
68b0be27-a7bd-4e1e-af9f-7eb5e058576c
Heymsfield, Steven B.
2710bc2e-4aa4-465e-b98e-b48d331926de
Kral, John G.
5fe90e5a-052e-40bd-a492-d0fe6ee551c9
Launer, Lenore J.
18e5f9c5-e5ec-4adf-820f-4eb390cac7a3
Penninger, Josef
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Phillips, David I. W.
29b73be7-2ff9-4fff-ae42-d59842df4cc6
Scarmeas, Nikolaos
754d2151-7755-4695-9544-a4a745dd66df
Fielding, Roger A.
36b26592-ce59-4443-ab26-185919da78c0
Gunstad, John
3616be66-fb84-4505-a649-5dfb4ba2af88
Gustafson, Deborah R.
68b0be27-a7bd-4e1e-af9f-7eb5e058576c
Heymsfield, Steven B.
2710bc2e-4aa4-465e-b98e-b48d331926de
Kral, John G.
5fe90e5a-052e-40bd-a492-d0fe6ee551c9
Launer, Lenore J.
18e5f9c5-e5ec-4adf-820f-4eb390cac7a3
Penninger, Josef
d5c70656-298f-4ff5-b4bb-221137703f01
Phillips, David I. W.
29b73be7-2ff9-4fff-ae42-d59842df4cc6
Scarmeas, Nikolaos
754d2151-7755-4695-9544-a4a745dd66df

Fielding, Roger A., Gunstad, John, Gustafson, Deborah R., Heymsfield, Steven B., Kral, John G., Launer, Lenore J., Penninger, Josef, Phillips, David I. W. and Scarmeas, Nikolaos (2013) The paradox of overnutrition in aging and cognition. [in special issue: Annals Meeting Reports] Annals of the New York Academy of Sciences, 1287 (1), 31-43. (doi:10.1111/nyas.12138). (PMID:23682739)

Record type: Article

Abstract

Populations of many countries are becoming increasingly overweight and obese, driven largely by excessive calorie intake and reduced physical activity; greater body mass is accompanied by epidemic levels of comorbid metabolic diseases. At the same time, individuals are living longer. The combination of aging and the increased prevalence of metabolic disease is associated with increases in aging-related comorbid diseases such as Alzheimer's disease, cerebrovascular dementia, and sarcopenia. Here, correlative and causal links between diseases of overnutrition and diseases of aging and cognition are explored.

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e-pub ahead of print date: 17 May 2013
Keywords: overnutrition, obesity, cognitive decline, Alzheimer’s disease, sarcopenia
Organisations: Human Development & Health

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Local EPrints ID: 355172
URI: http://eprints.soton.ac.uk/id/eprint/355172
ISSN: 0077-8923
PURE UUID: 019c2922-6aae-4e0d-9d42-b3a0f5eb24df

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Date deposited: 09 Aug 2013 11:48
Last modified: 27 Oct 2023 02:59

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Contributors

Author: Roger A. Fielding
Author: John Gunstad
Author: Deborah R. Gustafson
Author: Steven B. Heymsfield
Author: John G. Kral
Author: Lenore J. Launer
Author: Josef Penninger
Author: David I. W. Phillips
Author: Nikolaos Scarmeas

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