The University of Southampton
University of Southampton Institutional Repository
Warning ePrints Soton is experiencing an issue with some file downloads not being available. We are working hard to fix this. Please bear with us.

Estrogen treatment effects on cognition, memory and mood in male-to-female transsexuals

Estrogen treatment effects on cognition, memory and mood in male-to-female transsexuals
Estrogen treatment effects on cognition, memory and mood in male-to-female transsexuals
Gonadal hormones, particularly estrogens, have been suggested to influence memory and cognitive tasks that show sex differences. Previously, we reported that male-to-female (M–F) transsexuals undergoing estrogen treatment for sex re-assignment scored higher on verbal Paired Associate Learning (PAL) than a transsexual control group awaiting estrogen treatment. The present study used a more robust design to examine further associations between estrogen and cognition. We assessed additional aspects of memory, including visual, spatial, object and location memory, other cognitive abilities that show reliable sex differences, including verbal and visual–spatial abilities, and mood variables that could mediate associations between estrogen and cognition. In addition to comparing groups of individuals on and off estrogen, we used two repeated measures designs (AB and BA). The AB group was tested prior to hormone treatment and then again after treatment had begun; the BA group was tested while on estrogen treatment and then again when hormones had been withdrawn prior to surgery. Few changes in memory or cognition were observed, and changes that were observed were not consistent across study designs. The lack of significant effects did not relate to mood changes or to the sexual orientation of participants. These findings suggest that estrogen treatment associated with sex change for M–F transsexuals has little or no influence on sex-typed aspects of cognition or memory
0018-506X
708-717
Miles, Clare L.
2c3cd0e5-1aaf-46b6-8228-188c843bad4e
Green, Richard
3a732e39-d8f1-4537-8569-b62b3f81ceac
Hines, Melissa
2042e4fa-3d6e-4ee1-8ff4-5ad107414537
Miles, Clare L.
2c3cd0e5-1aaf-46b6-8228-188c843bad4e
Green, Richard
3a732e39-d8f1-4537-8569-b62b3f81ceac
Hines, Melissa
2042e4fa-3d6e-4ee1-8ff4-5ad107414537

Miles, Clare L., Green, Richard and Hines, Melissa (2006) Estrogen treatment effects on cognition, memory and mood in male-to-female transsexuals. Hormones and Behavior, 50 (5), 708-717. (doi:10.1016/j.yhbeh.2006.06.008). (PMID:16884726)

Record type: Article

Abstract

Gonadal hormones, particularly estrogens, have been suggested to influence memory and cognitive tasks that show sex differences. Previously, we reported that male-to-female (M–F) transsexuals undergoing estrogen treatment for sex re-assignment scored higher on verbal Paired Associate Learning (PAL) than a transsexual control group awaiting estrogen treatment. The present study used a more robust design to examine further associations between estrogen and cognition. We assessed additional aspects of memory, including visual, spatial, object and location memory, other cognitive abilities that show reliable sex differences, including verbal and visual–spatial abilities, and mood variables that could mediate associations between estrogen and cognition. In addition to comparing groups of individuals on and off estrogen, we used two repeated measures designs (AB and BA). The AB group was tested prior to hormone treatment and then again after treatment had begun; the BA group was tested while on estrogen treatment and then again when hormones had been withdrawn prior to surgery. Few changes in memory or cognition were observed, and changes that were observed were not consistent across study designs. The lack of significant effects did not relate to mood changes or to the sexual orientation of participants. These findings suggest that estrogen treatment associated with sex change for M–F transsexuals has little or no influence on sex-typed aspects of cognition or memory

This record has no associated files available for download.

More information

Published date: December 2006
Organisations: Psychology

Identifiers

Local EPrints ID: 355332
URI: http://eprints.soton.ac.uk/id/eprint/355332
ISSN: 0018-506X
PURE UUID: 3a96acaa-78b0-4bdc-a5da-9fdc7ad54e93

Catalogue record

Date deposited: 15 Aug 2013 14:07
Last modified: 09 Nov 2021 00:14

Export record

Altmetrics

Contributors

Author: Clare L. Miles
Author: Richard Green
Author: Melissa Hines

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×