The accumulation of deleterious mutations within the frozen niche variation hypothesis
The accumulation of deleterious mutations within the frozen niche variation hypothesis
The frozen niche variation hypothesis proposes that asexual clones exploit a fraction of a total resource niche available to the sexual population from which they arise. Differences in niche breadth may allow a period of coexistence between a sexual population and the faster reproducing asexual clones. Here, we model the longer term threat to the persistence of the sexual population from an accumulation of clonal diversity, balanced by the cost to the asexual population resulting from a faster rate of accumulation of deleterious mutations. We use Monte-Carlo simulations to quantify the interaction of niche breadth with accumulating deleterious mutations. These two mechanisms may act synergistically to prevent the extinction of the sexual population, given: (1) sufficient genetic variation, and consequently niche breadth, in the sexual population; (2) a relatively slow rate of accumulation of genetic diversity in the clonal population; (3) synergistic epistasis in the accumulation of deleterious mutations.
cost of males, cost of sex, evolution of sex, muller’s ratchet, very slightly deleterious mutations
651-662
Pound, G.E.
04a90e67-652b-4435-8b4b-ac70afb67ca5
Cox, S.J.
0e62aaed-24ad-4a74-b996-f606e40e5c55
Doncaster, C.P.
0eff2f42-fa0a-4e35-b6ac-475ad3482047
May 2004
Pound, G.E.
04a90e67-652b-4435-8b4b-ac70afb67ca5
Cox, S.J.
0e62aaed-24ad-4a74-b996-f606e40e5c55
Doncaster, C.P.
0eff2f42-fa0a-4e35-b6ac-475ad3482047
Pound, G.E., Cox, S.J. and Doncaster, C.P.
(2004)
The accumulation of deleterious mutations within the frozen niche variation hypothesis.
Journal of Evolutionary Biology, 17 (3), .
(doi:10.1111/j.1420-9101.2003.00690.x).
Abstract
The frozen niche variation hypothesis proposes that asexual clones exploit a fraction of a total resource niche available to the sexual population from which they arise. Differences in niche breadth may allow a period of coexistence between a sexual population and the faster reproducing asexual clones. Here, we model the longer term threat to the persistence of the sexual population from an accumulation of clonal diversity, balanced by the cost to the asexual population resulting from a faster rate of accumulation of deleterious mutations. We use Monte-Carlo simulations to quantify the interaction of niche breadth with accumulating deleterious mutations. These two mechanisms may act synergistically to prevent the extinction of the sexual population, given: (1) sufficient genetic variation, and consequently niche breadth, in the sexual population; (2) a relatively slow rate of accumulation of genetic diversity in the clonal population; (3) synergistic epistasis in the accumulation of deleterious mutations.
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Published date: May 2004
Keywords:
cost of males, cost of sex, evolution of sex, muller’s ratchet, very slightly deleterious mutations
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Local EPrints ID: 35562
URI: http://eprints.soton.ac.uk/id/eprint/35562
ISSN: 1010-061X
PURE UUID: 43e7ff5c-f978-426d-b1a4-d5b65d52c974
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Date deposited: 19 May 2006
Last modified: 16 Mar 2024 02:49
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Author:
G.E. Pound
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