The University of Southampton
University of Southampton Institutional Repository

Identification of viable embryos by noninvasive measurement of amino acids in culture media

Identification of viable embryos by noninvasive measurement of amino acids in culture media
Identification of viable embryos by noninvasive measurement of amino acids in culture media
This chapter highlights many important roles of amino acids for human preimplantation embryos. Amino acids are not only beneficial to embryo development but their utilisation by the embryo is also predictive of future viability, genetic health, DNA damage and trophectoderm integrity. These findings were remarkable and highlight how integral amino acids are to the physiology of the embryo. Thus, it is important that much consideration is given to the media used in clinical IVF. This will require suppliers to provide details of media formulations so that informed choices can be made. The use of amino acid profiling in a clinical setting offers the exciting prospect to nonsubjectively select the most developmentally competent embryo for transfer with the greatest chance of producing a live birth.
reproductive medicine, obstetrics/perinatology, gynecology
978-1-4614-6650-5
267-273
Springer
Houghton, Franchesca D.
53946041-127e-45a8-9edb-bf4b3c23005f
Gardner, David K.
Sakkas, Denny
Seli, Emre
Wells, Dagan
Houghton, Franchesca D.
53946041-127e-45a8-9edb-bf4b3c23005f
Gardner, David K.
Sakkas, Denny
Seli, Emre
Wells, Dagan

Houghton, Franchesca D. (2013) Identification of viable embryos by noninvasive measurement of amino acids in culture media. In, Gardner, David K., Sakkas, Denny, Seli, Emre and Wells, Dagan (eds.) Human Gametes and Preimplantation Embryos Assessment and Diagnosis. Springer, pp. 267-273. (doi:10.1007/978-1-4614-6651-2_24).

Record type: Book Section

Abstract

This chapter highlights many important roles of amino acids for human preimplantation embryos. Amino acids are not only beneficial to embryo development but their utilisation by the embryo is also predictive of future viability, genetic health, DNA damage and trophectoderm integrity. These findings were remarkable and highlight how integral amino acids are to the physiology of the embryo. Thus, it is important that much consideration is given to the media used in clinical IVF. This will require suppliers to provide details of media formulations so that informed choices can be made. The use of amino acid profiling in a clinical setting offers the exciting prospect to nonsubjectively select the most developmentally competent embryo for transfer with the greatest chance of producing a live birth.

This record has no associated files available for download.

More information

Published date: 2013
Keywords: reproductive medicine, obstetrics/perinatology, gynecology
Organisations: Human Development & Health

Identifiers

Local EPrints ID: 355746
URI: http://eprints.soton.ac.uk/id/eprint/355746
ISBN: 978-1-4614-6650-5
PURE UUID: 24869210-83d8-438f-a257-f6794033ea88
ORCID for Franchesca D. Houghton: ORCID iD orcid.org/0000-0002-5167-1694

Catalogue record

Date deposited: 05 Sep 2013 08:31
Last modified: 23 Jul 2022 01:55

Export record

Altmetrics

Contributors

Editor: David K. Gardner
Editor: Denny Sakkas
Editor: Emre Seli
Editor: Dagan Wells

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×