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Identification of viable embryos by noninvasive measurement of amino acids in culture media

Identification of viable embryos by noninvasive measurement of amino acids in culture media
Identification of viable embryos by noninvasive measurement of amino acids in culture media
This chapter highlights many important roles of amino acids for human preimplantation embryos. Amino acids are not only beneficial to embryo development but their utilisation by the embryo is also predictive of future viability, genetic health, DNA damage and trophectoderm integrity. These findings were remarkable and highlight how integral amino acids are to the physiology of the embryo. Thus, it is important that much consideration is given to the media used in clinical IVF. This will require suppliers to provide details of media formulations so that informed choices can be made. The use of amino acid profiling in a clinical setting offers the exciting prospect to nonsubjectively select the most developmentally competent embryo for transfer with the greatest chance of producing a live birth.
reproductive medicine, obstetrics/perinatology, gynecology
978-1-4614-6650-5
267-273
Springer
Houghton, Franchesca D.
53946041-127e-45a8-9edb-bf4b3c23005f
Gardner, David K.
Sakkas, Denny
Seli, Emre
Wells, Dagan
Houghton, Franchesca D.
53946041-127e-45a8-9edb-bf4b3c23005f
Gardner, David K.
Sakkas, Denny
Seli, Emre
Wells, Dagan

Houghton, Franchesca D. (2013) Identification of viable embryos by noninvasive measurement of amino acids in culture media. In, Gardner, David K., Sakkas, Denny, Seli, Emre and Wells, Dagan (eds.) Human Gametes and Preimplantation Embryos Assessment and Diagnosis. Springer, pp. 267-273. (doi:10.1007/978-1-4614-6651-2_24).

Record type: Book Section

Abstract

This chapter highlights many important roles of amino acids for human preimplantation embryos. Amino acids are not only beneficial to embryo development but their utilisation by the embryo is also predictive of future viability, genetic health, DNA damage and trophectoderm integrity. These findings were remarkable and highlight how integral amino acids are to the physiology of the embryo. Thus, it is important that much consideration is given to the media used in clinical IVF. This will require suppliers to provide details of media formulations so that informed choices can be made. The use of amino acid profiling in a clinical setting offers the exciting prospect to nonsubjectively select the most developmentally competent embryo for transfer with the greatest chance of producing a live birth.

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More information

Published date: 2013
Keywords: reproductive medicine, obstetrics/perinatology, gynecology
Organisations: Human Development & Health

Identifiers

Local EPrints ID: 355746
URI: http://eprints.soton.ac.uk/id/eprint/355746
ISBN: 978-1-4614-6650-5
PURE UUID: 24869210-83d8-438f-a257-f6794033ea88
ORCID for Franchesca D. Houghton: ORCID iD orcid.org/0000-0002-5167-1694

Catalogue record

Date deposited: 05 Sep 2013 08:31
Last modified: 15 Mar 2024 03:25

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Contributors

Editor: David K. Gardner
Editor: Denny Sakkas
Editor: Emre Seli
Editor: Dagan Wells

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