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Pregnancy and birth cohort resources in europe: a large opportunity for aetiological child health research

Pregnancy and birth cohort resources in europe: a large opportunity for aetiological child health research
Pregnancy and birth cohort resources in europe: a large opportunity for aetiological child health research
Background: During the past 25 years, many pregnancy and birth cohorts have been established. Each cohort provides unique opportunities for examining associations of early-life exposures with child development and health. However, to fully exploit the large amount of available resources and to facilitate cross-cohort collaboration, it is necessary to have accessible information on each cohort and its individual characteristics. The aim of this work was to provide an overview of European pregnancy and birth cohorts registered in a freely accessible database located at http://www.birthcohorts.net.

Methods: European pregnancy and birth cohorts initiated in 1980 or later with at least 300 mother–child pairs enrolled during pregnancy or at birth, and with postnatal data, were eligible for inclusion. Eligible cohorts were invited to provide information on the data and biological samples collected, as well as the timing of data collection.

Results: In total, 70 cohorts were identified. Of these, 56 fulfilled the inclusion criteria encompassing a total of more than 500?000 live-born European children. The cohorts represented 19 countries with the majority of cohorts located in Northern and Western Europe. Some cohorts were general with multiple aims, whilst others focused on specific health or exposure-related research questions.

Conclusion: This work demonstrates a great potential for cross-cohort collaboration addressing important aspects of child health. The web site, http://www.birthcohorts.net, proved to be a useful tool for accessing information on European pregnancy and birth cohorts and their characteristics.
european pregnancy birth cohort, cohort characteristics, cross-cohort collaboration
0269-5022
393-414
Larsen, Pernille Stemann
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Barros, Henrique
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Brophy, Sinead
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Porta, Daniela
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Poulsen, Gry
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Richiardi, Lorenzo
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Roeleveld, Nel
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Skovgaard, Anne Mette
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Sram, Radim J.
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Strandberg-Larsen, Katrine
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Thijs, Carel
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Van Eijsden, Manon
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Larsen, Pernille Stemann
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Kamper-Jørgensen, Mads
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Adamson, Ashley
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Barros, Henrique
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Bonde, Jens Peter
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Brescianini, Sonia
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Brophy, Sinead
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Casas, Maribel
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Devereux, Graham
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Eggesbø, Merete
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Fantini, Maria Pia
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Frey, Urs
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Gehring, Ulrike
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Henriksen, Tine Brink
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Heude, Barbara
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Kull, Inger
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Kyhl, Henriette Boye
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Magnus, Per
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Momas, Isabelle
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Murray, Dierdre
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Thijs, Carel
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Van Eijsden, Manon
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Wright, John
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Vrijheid, Martine
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Andersen, Anne-Marie Nybo
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Larsen, Pernille Stemann, Kamper-Jørgensen, Mads, Adamson, Ashley, Barros, Henrique, Bonde, Jens Peter, Brescianini, Sonia, Brophy, Sinead, Casas, Maribel, Devereux, Graham, Eggesbø, Merete, Fantini, Maria Pia, Frey, Urs, Gehring, Ulrike, Grazuleviciene, Regina, Henriksen, Tine Brink, Hertz-Picciotto, Irva, Heude, Barbara, Hryhorczuk, Daniel O., Inskip, Hazel, Jaddoe, Vincent W.V., Lawlor, Debbie A., Ludvigsson, Johnny, Kelleher, Cecily, Kiess, Wieland, Koletzko, Berthold, Kuehni, Claudia Elisabeth, Kull, Inger, Kyhl, Henriette Boye, Magnus, Per, Momas, Isabelle, Murray, Dierdre, Pekkanen, Juha, Polanska, Kinga, Porta, Daniela, Poulsen, Gry, Richiardi, Lorenzo, Roeleveld, Nel, Skovgaard, Anne Mette, Sram, Radim J., Strandberg-Larsen, Katrine, Thijs, Carel, Van Eijsden, Manon, Wright, John, Vrijheid, Martine and Andersen, Anne-Marie Nybo (2013) Pregnancy and birth cohort resources in europe: a large opportunity for aetiological child health research. Paediatric and Perinatal Epidemiology, 27 (4), 393-414. (doi:10.1111/ppe.12060). (PMID:23772942)

Record type: Article

Abstract

Background: During the past 25 years, many pregnancy and birth cohorts have been established. Each cohort provides unique opportunities for examining associations of early-life exposures with child development and health. However, to fully exploit the large amount of available resources and to facilitate cross-cohort collaboration, it is necessary to have accessible information on each cohort and its individual characteristics. The aim of this work was to provide an overview of European pregnancy and birth cohorts registered in a freely accessible database located at http://www.birthcohorts.net.

Methods: European pregnancy and birth cohorts initiated in 1980 or later with at least 300 mother–child pairs enrolled during pregnancy or at birth, and with postnatal data, were eligible for inclusion. Eligible cohorts were invited to provide information on the data and biological samples collected, as well as the timing of data collection.

Results: In total, 70 cohorts were identified. Of these, 56 fulfilled the inclusion criteria encompassing a total of more than 500?000 live-born European children. The cohorts represented 19 countries with the majority of cohorts located in Northern and Western Europe. Some cohorts were general with multiple aims, whilst others focused on specific health or exposure-related research questions.

Conclusion: This work demonstrates a great potential for cross-cohort collaboration addressing important aspects of child health. The web site, http://www.birthcohorts.net, proved to be a useful tool for accessing information on European pregnancy and birth cohorts and their characteristics.

Full text not available from this repository.

More information

e-pub ahead of print date: 17 June 2013
Published date: July 2013
Keywords: european pregnancy birth cohort, cohort characteristics, cross-cohort collaboration
Organisations: Faculty of Medicine

Identifiers

Local EPrints ID: 356071
URI: http://eprints.soton.ac.uk/id/eprint/356071
ISSN: 0269-5022
PURE UUID: a22ef663-0416-4b8e-a3b1-7b8ed8bd7590
ORCID for Hazel Inskip: ORCID iD orcid.org/0000-0001-8897-1749

Catalogue record

Date deposited: 10 Sep 2013 13:20
Last modified: 12 Nov 2019 01:58

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Contributors

Author: Pernille Stemann Larsen
Author: Mads Kamper-Jørgensen
Author: Ashley Adamson
Author: Henrique Barros
Author: Jens Peter Bonde
Author: Sonia Brescianini
Author: Sinead Brophy
Author: Maribel Casas
Author: Graham Devereux
Author: Merete Eggesbø
Author: Maria Pia Fantini
Author: Urs Frey
Author: Ulrike Gehring
Author: Regina Grazuleviciene
Author: Tine Brink Henriksen
Author: Irva Hertz-Picciotto
Author: Barbara Heude
Author: Daniel O. Hryhorczuk
Author: Hazel Inskip ORCID iD
Author: Vincent W.V. Jaddoe
Author: Debbie A. Lawlor
Author: Johnny Ludvigsson
Author: Cecily Kelleher
Author: Wieland Kiess
Author: Berthold Koletzko
Author: Claudia Elisabeth Kuehni
Author: Inger Kull
Author: Henriette Boye Kyhl
Author: Per Magnus
Author: Isabelle Momas
Author: Dierdre Murray
Author: Juha Pekkanen
Author: Kinga Polanska
Author: Daniela Porta
Author: Gry Poulsen
Author: Lorenzo Richiardi
Author: Nel Roeleveld
Author: Anne Mette Skovgaard
Author: Radim J. Sram
Author: Katrine Strandberg-Larsen
Author: Carel Thijs
Author: Manon Van Eijsden
Author: John Wright
Author: Martine Vrijheid
Author: Anne-Marie Nybo Andersen

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