Letter. Absence of surface CD27 distinguishes hairy cell leukemia from other leukemic B-cell malignancies

Forconi, Francesco, Raspadori, Donatella, Lenoci, Mariapia and Lauria, Francesco (2005) Letter. Absence of surface CD27 distinguishes hairy cell leukemia from other leukemic B-cell malignancies. Haematologica, 90 (2), 266-268. (PMID:15710587)

Record type: Article

Abstract

Surface expression of CD27 was evaluated in 75 mature leukemic B-cell neoplasms. All cases other than hairy cell leukemia (HCL) expressed CD27. Intensity was significantly higher in chronic lymphocytic leukemia. Lack of CD27 in 17/17 HCL contrasted with expression of this marker in 5/5 splenic lymphomas with villous lymphocytes. Lack of CD27 is a new distinctive feature of HCL among B-cell malignancies.

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Published date: February 2005

Organisations: Cancer Sciences

Identifiers

Local EPrints ID: 358173

URI: http://eprints.soton.ac.uk/id/eprint/358173

ISSN: 0390-6078

PURE UUID: 1eaa11cc-8d00-49bb-9595-413959464802

ORCID for Francesco Forconi:

orcid.org/0000-0002-2211-1831

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Date deposited: 22 Oct 2013 13:24

Last modified: 24 Nov 2022 02:44

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Contributors

Author: Francesco Forconi

Author: Donatella Raspadori

Author: Mariapia Lenoci

Author: Francesco Lauria

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