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CD30 positive (non-anaplastic) peripheral T-cell lymphoma of the thyroid gland

CD30 positive (non-anaplastic) peripheral T-cell lymphoma of the thyroid gland
CD30 positive (non-anaplastic) peripheral T-cell lymphoma of the thyroid gland
Primary non-Hodgkin's lymphoma of the thyroid gland are infrequent tumors. They almost exclusively derive from B cells of mucosa-associated lymphatic tissue and only a very small minority of them is represented by T cell lymphomas. CD30 molecule, other than in Hodgkin's and Redd-Sternberg' cells, is strictly associated with anaplastic large cell lymphoma and ALK lymphomas, the latter being identified by the monoclonal antibody ALK1. We report a case of CD30-positive non-anaplastic (ALK1-negative) peripheral T cell lymphoma of the thyroid gland and speculate on aspects concerning diagnosis and the morphologic and immunohistochemical findings.
thyroid, NHL, ALK1, CD30, non-anaplastic
0390-6078
946-948
Forconi, Francesco
ce9ed873-58cf-4876-bf3a-9ba1d163edc8
Bocchia, Monica
55dbb34d-ab5d-4828-a4a4-a1fef1b41bb6
Marconcini, Silvia
8005d8d3-417e-4662-8568-8bd4415301b4
Bigazzi, Catia
8c830e99-b779-4375-b043-df4ce7708604
Milani, Marina
3d18f861-f2d2-43a0-b951-1b2272ab5c42
Fraternali-Orcioni, Giulio
04aa669e-6f43-41cb-9b24-e3439d245b5a
Lauria, Franceso
e0a69244-78fd-46ff-93cb-179ef0d0fabb
Forconi, Francesco
ce9ed873-58cf-4876-bf3a-9ba1d163edc8
Bocchia, Monica
55dbb34d-ab5d-4828-a4a4-a1fef1b41bb6
Marconcini, Silvia
8005d8d3-417e-4662-8568-8bd4415301b4
Bigazzi, Catia
8c830e99-b779-4375-b043-df4ce7708604
Milani, Marina
3d18f861-f2d2-43a0-b951-1b2272ab5c42
Fraternali-Orcioni, Giulio
04aa669e-6f43-41cb-9b24-e3439d245b5a
Lauria, Franceso
e0a69244-78fd-46ff-93cb-179ef0d0fabb

Forconi, Francesco, Bocchia, Monica, Marconcini, Silvia, Bigazzi, Catia, Milani, Marina, Fraternali-Orcioni, Giulio and Lauria, Franceso (1999) CD30 positive (non-anaplastic) peripheral T-cell lymphoma of the thyroid gland. Haematologica, 84 (10), 946-948. (PMID:10509044)

Record type: Article

Abstract

Primary non-Hodgkin's lymphoma of the thyroid gland are infrequent tumors. They almost exclusively derive from B cells of mucosa-associated lymphatic tissue and only a very small minority of them is represented by T cell lymphomas. CD30 molecule, other than in Hodgkin's and Redd-Sternberg' cells, is strictly associated with anaplastic large cell lymphoma and ALK lymphomas, the latter being identified by the monoclonal antibody ALK1. We report a case of CD30-positive non-anaplastic (ALK1-negative) peripheral T cell lymphoma of the thyroid gland and speculate on aspects concerning diagnosis and the morphologic and immunohistochemical findings.

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More information

Published date: October 1999
Keywords: thyroid, NHL, ALK1, CD30, non-anaplastic
Organisations: Cancer Sciences

Identifiers

Local EPrints ID: 358189
URI: http://eprints.soton.ac.uk/id/eprint/358189
ISSN: 0390-6078
PURE UUID: 17010e20-eb83-4e3c-8a3f-ceeddd92e7e4

Catalogue record

Date deposited: 12 Nov 2013 11:18
Last modified: 16 Jul 2019 21:21

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Contributors

Author: Monica Bocchia
Author: Silvia Marconcini
Author: Catia Bigazzi
Author: Marina Milani
Author: Giulio Fraternali-Orcioni
Author: Franceso Lauria

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