High-resolution NMR spectroscopy on a chip by structural
compensation of magnetic susceptibility mismatch
High-resolution NMR spectroscopy on a chip by structural
compensation of magnetic susceptibility mismatch
Microfluidic compensation structures are introduced as a tool to homogenize magnetic field gradients present in microfluidic NMR spectroscopy. Magnetic field distortions are eliminated by compensating the magnetic susceptibility mismatch between the sample fluid and chip material through additional, lithographically defined compensation structures. This strategy will allow high resolution NMR spectroscopy on a chip, enabling a range of metabolomic applications.
Ryan, Herbert
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Landers, James P.
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Begley, Matthew R.
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Utz, Marcel
c84ed64c-9e89-4051-af39-d401e423891b
October 2012
Ryan, Herbert
4beece80-5254-409f-b21d-f3a962316360
Landers, James P.
f85edaa2-5c24-4f2d-be3d-c84e631833ad
Begley, Matthew R.
9f4e52bc-507a-4ef6-910f-bd11d25c2209
Utz, Marcel
c84ed64c-9e89-4051-af39-d401e423891b
Ryan, Herbert, Landers, James P., Begley, Matthew R. and Utz, Marcel
(2012)
High-resolution NMR spectroscopy on a chip by structural
compensation of magnetic susceptibility mismatch.
16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Okinawa, Japan.
27 Oct - 01 Nov 2012.
Record type:
Conference or Workshop Item
(Paper)
Abstract
Microfluidic compensation structures are introduced as a tool to homogenize magnetic field gradients present in microfluidic NMR spectroscopy. Magnetic field distortions are eliminated by compensating the magnetic susceptibility mismatch between the sample fluid and chip material through additional, lithographically defined compensation structures. This strategy will allow high resolution NMR spectroscopy on a chip, enabling a range of metabolomic applications.
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More information
Published date: October 2012
Venue - Dates:
16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Okinawa, Japan, 2012-10-27 - 2012-11-01
Organisations:
Chemistry, Faculty of Natural and Environmental Sciences, Magnetic Resonance
Identifiers
Local EPrints ID: 360219
URI: http://eprints.soton.ac.uk/id/eprint/360219
PURE UUID: 2d143e0b-14e4-4cc9-b752-aff5ab6a9097
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Date deposited: 29 Nov 2013 14:15
Last modified: 09 Jan 2022 03:41
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Contributors
Author:
Herbert Ryan
Author:
James P. Landers
Author:
Matthew R. Begley
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