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High-resolution NMR spectroscopy on a chip by structural compensation of magnetic susceptibility mismatch

High-resolution NMR spectroscopy on a chip by structural compensation of magnetic susceptibility mismatch
High-resolution NMR spectroscopy on a chip by structural compensation of magnetic susceptibility mismatch
Microfluidic compensation structures are introduced as a tool to homogenize magnetic field gradients present in microfluidic NMR spectroscopy. Magnetic field distortions are eliminated by compensating the magnetic susceptibility mismatch between the sample fluid and chip material through additional, lithographically defined compensation structures. This strategy will allow high resolution NMR spectroscopy on a chip, enabling a range of metabolomic applications.
Ryan, Herbert
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Landers, James P.
f85edaa2-5c24-4f2d-be3d-c84e631833ad
Begley, Matthew R.
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Utz, Marcel
c84ed64c-9e89-4051-af39-d401e423891b
Ryan, Herbert
4beece80-5254-409f-b21d-f3a962316360
Landers, James P.
f85edaa2-5c24-4f2d-be3d-c84e631833ad
Begley, Matthew R.
9f4e52bc-507a-4ef6-910f-bd11d25c2209
Utz, Marcel
c84ed64c-9e89-4051-af39-d401e423891b

Ryan, Herbert, Landers, James P., Begley, Matthew R. and Utz, Marcel (2012) High-resolution NMR spectroscopy on a chip by structural compensation of magnetic susceptibility mismatch. 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Japan. 28 Oct - 01 Nov 2012.

Record type: Conference or Workshop Item (Paper)

Abstract

Microfluidic compensation structures are introduced as a tool to homogenize magnetic field gradients present in microfluidic NMR spectroscopy. Magnetic field distortions are eliminated by compensating the magnetic susceptibility mismatch between the sample fluid and chip material through additional, lithographically defined compensation structures. This strategy will allow high resolution NMR spectroscopy on a chip, enabling a range of metabolomic applications.

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More information

Published date: October 2012
Venue - Dates: 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Japan, 2012-10-28 - 2012-11-01
Organisations: Chemistry, Faculty of Natural and Environmental Sciences, Magnetic Resonance

Identifiers

Local EPrints ID: 360219
URI: http://eprints.soton.ac.uk/id/eprint/360219
PURE UUID: 2d143e0b-14e4-4cc9-b752-aff5ab6a9097
ORCID for Marcel Utz: ORCID iD orcid.org/0000-0003-2274-9672

Catalogue record

Date deposited: 29 Nov 2013 14:15
Last modified: 20 Jul 2019 00:40

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Contributors

Author: Herbert Ryan
Author: James P. Landers
Author: Matthew R. Begley
Author: Marcel Utz ORCID iD

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