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Synthesis of homochiral R-(+)-2-methyl-1-butanol

Synthesis of homochiral R-(+)-2-methyl-1-butanol
Synthesis of homochiral R-(+)-2-methyl-1-butanol
R-(+)-2-Methylbutanol 10a, a building block of several natural products, is commercially unavailable. The total synthesis of 10a in four steps utilising the boronic ester homologation approach is described.
boron, stereoselective synthesis, homologation, boronic esters, 2-methylbutanol
1064-1070
Logothetis, Thomas A.
9f42a28f-0c36-4d47-a137-7a317acb0237
Vleggaar, Robert
9105cd07-ab60-4fc6-b668-7591f9606ecd
Logothetis, Thomas A.
9f42a28f-0c36-4d47-a137-7a317acb0237
Vleggaar, Robert
9105cd07-ab60-4fc6-b668-7591f9606ecd

Logothetis, Thomas A. and Vleggaar, Robert (2000) Synthesis of homochiral R-(+)-2-methyl-1-butanol. [in special issue: Proceedings of the 4th International Electronic Conference on Synthetic Organic Chemistry, 1-30 November 2000] Sciforum Electronic Conference Series, 4, 1064-1070.

Record type: Article

Abstract

R-(+)-2-Methylbutanol 10a, a building block of several natural products, is commercially unavailable. The total synthesis of 10a in four steps utilising the boronic ester homologation approach is described.

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More information

Published date: 2000
Venue - Dates: 4th Int. Electron. Conf. Synth. Org. Chem., 2000-01-01
Keywords: boron, stereoselective synthesis, homologation, boronic esters, 2-methylbutanol
Organisations: Chemistry

Identifiers

Local EPrints ID: 360742
URI: http://eprints.soton.ac.uk/id/eprint/360742
PURE UUID: ef8c4e05-35ee-490d-8738-ef1873f61133
ORCID for Thomas A. Logothetis: ORCID iD orcid.org/0000-0002-3437-5287

Catalogue record

Date deposited: 03 Jan 2014 16:20
Last modified: 10 Jul 2020 00:30

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