Construction of DNA–polymer hybrids using intercalation interactions
Construction of DNA–polymer hybrids using intercalation interactions
Reversible addition–fragmentation chain transfer (RAFT) polymerisation was used to produce a range of polymers terminated with an acridine group, which intercalates efficiently into dsDNA; the structure of the polymer determines the nature and strength of the interaction. Using a short 63 base pair dsDNA, discrete and well-defined DNA–polymer hybrid nanoparticles were formed, which were characterised by dynamic light scattering, small-angle X-ray scattering and atomic force microscopy
1338-1340
Wilks, Thomas R.
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Pitto-Barry, Anaïs
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Kirby, Nigel
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Stulz, Eugen
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O'Reilly, Rachel K.
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2014
Wilks, Thomas R.
f3e9f3ae-6f93-4a1b-89a0-6916e353aa24
Pitto-Barry, Anaïs
5ee2b8c8-34ec-4ac4-bceb-9ccc29063344
Kirby, Nigel
f096d265-c00e-42e0-8cd8-fb5ab470f513
Stulz, Eugen
9a6c04cf-32ca-442b-9281-bbf3d23c622d
O'Reilly, Rachel K.
086bc91e-2303-4543-b79c-ae16ada0b101
Wilks, Thomas R., Pitto-Barry, Anaïs, Kirby, Nigel, Stulz, Eugen and O'Reilly, Rachel K.
(2014)
Construction of DNA–polymer hybrids using intercalation interactions.
Chemical Communications, 50, .
(doi:10.1039/C3CC48726A).
Abstract
Reversible addition–fragmentation chain transfer (RAFT) polymerisation was used to produce a range of polymers terminated with an acridine group, which intercalates efficiently into dsDNA; the structure of the polymer determines the nature and strength of the interaction. Using a short 63 base pair dsDNA, discrete and well-defined DNA–polymer hybrid nanoparticles were formed, which were characterised by dynamic light scattering, small-angle X-ray scattering and atomic force microscopy
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Published date: 2014
Organisations:
Chemistry
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Local EPrints ID: 361088
URI: http://eprints.soton.ac.uk/id/eprint/361088
ISSN: 1359-7345
PURE UUID: 1b9a91a2-6ab5-4466-bea0-38565aa505c4
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Date deposited: 13 Jan 2014 13:25
Last modified: 20 Jul 2019 00:54
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Author:
Thomas R. Wilks
Author:
Anaïs Pitto-Barry
Author:
Nigel Kirby
Author:
Rachel K. O'Reilly
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