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Solid fuel use is a major risk factor for acute coronary syndromes among rural women: a matched case control study

Solid fuel use is a major risk factor for acute coronary syndromes among rural women: a matched case control study
Solid fuel use is a major risk factor for acute coronary syndromes among rural women: a matched case control study
Methods

Data were collected at a public tertiary care hospital in a rural district of Pakistan. Seventy-three women with ACS were compared with controls, individually matched for sex and age (±5 years), who were admitted to hospital for other reasons. Fuels used for cooking and exposures to potentially confounding variables were ascertained through a questionnaire administered at interview and measurement of height and weight. Conditional logistic regression was used to estimate odds ratios (ORs) with 95% confidence intervals (95% CIs).

Results

After adjustment for potential confounding factors, current use of solid fuel was strongly associated with ACS (OR 4.8, 95% CI: 1.5–14.8), and risk was lowest in women who had last used solid fuel more than 15 years earlier. The population attributable fraction for ACS in relation to current use of solid fuel was 49.0% (95% CI: 41.3%–57.4%).

Conclusions

These findings support the hypothesis that indoor air pollution from use of solid fuel is an important cause of ACS. Our study demonstrates the feasibility of case-control studies in rural populations of women to address this question, and is an encouragement to larger and statistically more powerful investigations.
acute coronary syndrome, biomass fuel, indoor air pollution, matched case control, risk factor, women
77-82
Fatmi, Z.
48090879-4399-4d7e-ae59-568fdc8154d2
Coggon, D.
2b43ce0a-cc61-4d86-b15d-794208ffa5d3
Kazi, A.
afa4a875-3a98-4b12-9dff-c56969de91b8
Naeem, I.
c4d2545c-e0d2-4c05-9399-35ab6c6a5e08
Kadir, M.M.
0c7a67cb-57f6-40b7-a944-c42b31943a94
Sathiakumar, N.
1187bc03-3371-45dd-acc7-cc01764cfa79
Fatmi, Z.
48090879-4399-4d7e-ae59-568fdc8154d2
Coggon, D.
2b43ce0a-cc61-4d86-b15d-794208ffa5d3
Kazi, A.
afa4a875-3a98-4b12-9dff-c56969de91b8
Naeem, I.
c4d2545c-e0d2-4c05-9399-35ab6c6a5e08
Kadir, M.M.
0c7a67cb-57f6-40b7-a944-c42b31943a94
Sathiakumar, N.
1187bc03-3371-45dd-acc7-cc01764cfa79

Fatmi, Z., Coggon, D., Kazi, A., Naeem, I., Kadir, M.M. and Sathiakumar, N. (2014) Solid fuel use is a major risk factor for acute coronary syndromes among rural women: a matched case control study. Public Health, 128 (1), 77-82. (doi:10.1016/j.puhe.2013.09.005). (PMID:24342134)

Record type: Article

Abstract

Methods

Data were collected at a public tertiary care hospital in a rural district of Pakistan. Seventy-three women with ACS were compared with controls, individually matched for sex and age (±5 years), who were admitted to hospital for other reasons. Fuels used for cooking and exposures to potentially confounding variables were ascertained through a questionnaire administered at interview and measurement of height and weight. Conditional logistic regression was used to estimate odds ratios (ORs) with 95% confidence intervals (95% CIs).

Results

After adjustment for potential confounding factors, current use of solid fuel was strongly associated with ACS (OR 4.8, 95% CI: 1.5–14.8), and risk was lowest in women who had last used solid fuel more than 15 years earlier. The population attributable fraction for ACS in relation to current use of solid fuel was 49.0% (95% CI: 41.3%–57.4%).

Conclusions

These findings support the hypothesis that indoor air pollution from use of solid fuel is an important cause of ACS. Our study demonstrates the feasibility of case-control studies in rural populations of women to address this question, and is an encouragement to larger and statistically more powerful investigations.

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More information

e-pub ahead of print date: 14 December 2013
Published date: January 2014
Keywords: acute coronary syndrome, biomass fuel, indoor air pollution, matched case control, risk factor, women
Organisations: Faculty of Medicine

Identifiers

Local EPrints ID: 361836
URI: http://eprints.soton.ac.uk/id/eprint/361836
PURE UUID: ee88117a-6d40-4f32-bbc7-54493afe9dc8
ORCID for D. Coggon: ORCID iD orcid.org/0000-0003-1930-3987

Catalogue record

Date deposited: 04 Feb 2014 15:14
Last modified: 24 Sep 2019 00:55

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Contributors

Author: Z. Fatmi
Author: D. Coggon ORCID iD
Author: A. Kazi
Author: I. Naeem
Author: M.M. Kadir
Author: N. Sathiakumar

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