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Meiosis: mouse eggs do their anaphase topsy-turvy

Meiosis: mouse eggs do their anaphase topsy-turvy
Meiosis: mouse eggs do their anaphase topsy-turvy
The meiotic separation of sister chromatids in mature metaphase II mouse eggs is observed to depend initially on spindle lengthening (Anaphase B), then on microtubule shortening (Anaphase A). Having Anaphase B precede Anaphase A may be the mechanism by which mammalian eggs can generate a haploid chromosome number but without the loss of too much cytoplasm.

0960-9822
437-444
Jones, KT
73e8e2b5-cd67-4691-b1a9-4e7bc9066af4
Jones, KT
73e8e2b5-cd67-4691-b1a9-4e7bc9066af4

Jones, KT (2012) Meiosis: mouse eggs do their anaphase topsy-turvy. Current Biology, 22 (5), 437-444. (doi:10.1016/j.cub.2012.01.047).

Record type: Article

Abstract

The meiotic separation of sister chromatids in mature metaphase II mouse eggs is observed to depend initially on spindle lengthening (Anaphase B), then on microtubule shortening (Anaphase A). Having Anaphase B precede Anaphase A may be the mechanism by which mammalian eggs can generate a haploid chromosome number but without the loss of too much cytoplasm.

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More information

Published date: 6 March 2012
Organisations: Centre for Biological Sciences
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Identifiers

Local EPrints ID: 361975
URI: http://eprints.soton.ac.uk/id/eprint/361975
DOI: doi:10.1016/j.cub.2012.01.047
ISSN: 0960-9822
PURE UUID: d627c09c-2411-4139-91a2-742cfb73aab4
ORCID for KT Jones: ORCID iD orcid.org/0000-0002-0294-0851

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Date deposited: 10 Feb 2014 12:10
Last modified: 14 Mar 2024 15:58

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Author: KT Jones ORCID iD

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