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FIN219, an auxin-regulated gene, defines a link between phytochrome A and the downstream regulator COP1 in light control of Arabidopsis development

FIN219, an auxin-regulated gene, defines a link between phytochrome A and the downstream regulator COP1 in light control of Arabidopsis development
FIN219, an auxin-regulated gene, defines a link between phytochrome A and the downstream regulator COP1 in light control of Arabidopsis development
Light signals perceived by photoreceptors are transduced to negatively regulate COP1, a key repressor of photomorphogenic development. To identify genes involved in light inactivation of COP1, a genetic screen was employed to identify extragenic modifier mutations of a temperature-sensitive cop1 allele. One suppressor mutation isolated also exhibited a far-red-specific long hypocotyl phenotype in a wild-type background. Further phenotypic analyses of this new mutation, named fin219, suggested that it defines a novel phytochrome A signaling component. Genetic analysis indicated that FIN219 interacts closely with another phytochrome A signaling component, FHY1. Molecular characterization of FIN219 indicated that it encodes a cytoplasmic localized protein highly similar to the GH3 family of proteins and its expression is rapidly induced by auxin. In contrast to its loss-of-function mutant phenotype, overexpression of FIN219 results in a far-red-specific hyperphotomorphogenic response. Our data suggest that FIN219 may define a critical link for phytochrome A-mediated far-red inactivation of COP1 and a possible cross-talk juncture between auxin regulation and phytochrome signaling.
arabidopsis development, COP1 repressor, FIN219 gene, light control, auxin regulation, phytochrome signaling
0890-9369
1958-1970
Hsieh, Hsu-Liang
173735c9-03d1-456c-af61-d8a77326a512
Okamoto, Haruko
cea35380-7618-44c8-a268-47b0198cc7f9
Wang, Mingli
e6acc39d-3241-477a-a564-5c855ede2bca
Ang, Lay-Hong
4189f1cd-53fc-40f7-96a5-655d7f6270f2
Matsui, Minami
85299349-b64d-40ac-8687-f59607cb63cb
Goodman, Horward
b322b487-32f6-4ba8-a1e2-af977967dff7
Deng, Xing Wang
4e1d848e-08c4-43d2-8a79-c42b062b742f
Hsieh, Hsu-Liang
173735c9-03d1-456c-af61-d8a77326a512
Okamoto, Haruko
cea35380-7618-44c8-a268-47b0198cc7f9
Wang, Mingli
e6acc39d-3241-477a-a564-5c855ede2bca
Ang, Lay-Hong
4189f1cd-53fc-40f7-96a5-655d7f6270f2
Matsui, Minami
85299349-b64d-40ac-8687-f59607cb63cb
Goodman, Horward
b322b487-32f6-4ba8-a1e2-af977967dff7
Deng, Xing Wang
4e1d848e-08c4-43d2-8a79-c42b062b742f

Hsieh, Hsu-Liang, Okamoto, Haruko, Wang, Mingli, Ang, Lay-Hong, Matsui, Minami, Goodman, Horward and Deng, Xing Wang (2000) FIN219, an auxin-regulated gene, defines a link between phytochrome A and the downstream regulator COP1 in light control of Arabidopsis development. Genes & Development, 14 (15), 1958-1970. (doi:10.1101/gad.14.15.1958). (PMID:10921909)

Record type: Article

Abstract

Light signals perceived by photoreceptors are transduced to negatively regulate COP1, a key repressor of photomorphogenic development. To identify genes involved in light inactivation of COP1, a genetic screen was employed to identify extragenic modifier mutations of a temperature-sensitive cop1 allele. One suppressor mutation isolated also exhibited a far-red-specific long hypocotyl phenotype in a wild-type background. Further phenotypic analyses of this new mutation, named fin219, suggested that it defines a novel phytochrome A signaling component. Genetic analysis indicated that FIN219 interacts closely with another phytochrome A signaling component, FHY1. Molecular characterization of FIN219 indicated that it encodes a cytoplasmic localized protein highly similar to the GH3 family of proteins and its expression is rapidly induced by auxin. In contrast to its loss-of-function mutant phenotype, overexpression of FIN219 results in a far-red-specific hyperphotomorphogenic response. Our data suggest that FIN219 may define a critical link for phytochrome A-mediated far-red inactivation of COP1 and a possible cross-talk juncture between auxin regulation and phytochrome signaling.

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More information

Published date: 1 August 2000
Keywords: arabidopsis development, COP1 repressor, FIN219 gene, light control, auxin regulation, phytochrome signaling
Organisations: Centre for Biological Sciences

Identifiers

Local EPrints ID: 362153
URI: http://eprints.soton.ac.uk/id/eprint/362153
ISSN: 0890-9369
PURE UUID: 7a7ddd17-2f66-46c5-941d-b2ad8b9793bf

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Date deposited: 11 Mar 2014 11:43
Last modified: 09 Nov 2021 01:00

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Contributors

Author: Hsu-Liang Hsieh
Author: Haruko Okamoto
Author: Mingli Wang
Author: Lay-Hong Ang
Author: Minami Matsui
Author: Horward Goodman
Author: Xing Wang Deng

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