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Development of a health index in patients with ankylosing spondylitis (ASAS HI): final result of a global initiative based on the ICF guided by ASAS

Development of a health index in patients with ankylosing spondylitis (ASAS HI): final result of a global initiative based on the ICF guided by ASAS
Development of a health index in patients with ankylosing spondylitis (ASAS HI): final result of a global initiative based on the ICF guided by ASAS
Objectives The burden of disease in patients with ankylosing spondylitis (AS) can be considerable. However, no agreement has been reached among expert members of Assessment of SpondyloArthritis International Society (ASAS) to define severity of AS. Based on the International Classification of Functioning, Disability and Health (ICF), a core set of items for AS has been selected to represent the entire spectrum of possible problems in functioning. Based on this, the objective of this study was to develop a tool to quantify health in AS, the ASAS Health Index.

Methods First, based on a literature search, experts’ and patients’ opinion, a large item pool covering the categories of the ICF core set was generated. In several steps this item pool was reduced based on reliability, Rasch analysis and consensus building after two cross-sectional surveys to come up with the best fitting items representing most categories of the ICF core set for AS.

Results After the first survey with 1754 patients, the item pool of 251 items was reduced to 82. After selection by an expert committee, 50 items remained which were tested in a second cross-sectional survey. The results were used to reduce the number of items to a final set of 17 items. This selection showed the best reliability and fit to the Rasch model, no residual correlation, and absence of consistent differential item function and a Person Separation Index of 0.82.

Conclusions In this long sequential study, 17 items which cover most of the ICF core set were identified that showed the best representation of the health status of patients with AS. The ASAS Health Index is a linear composite measure which differs from other measures in the public domain.
0003-4967
830-835
Kiltz, U.
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van der Heijde, D.
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Boonen, A.
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Cieza, A.
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Stucki, G.
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Khan, M.A.
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Maksymowych, W.P.
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Marzo-Ortega, H.
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Reveille, J.
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Stebbings, S.
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Bostan, C.
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Braun, J.
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Kiltz, U.
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van der Heijde, D.
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Boonen, A.
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Cieza, A.
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Stucki, G.
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Khan, M.A.
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Maksymowych, W.P.
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Marzo-Ortega, H.
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Reveille, J.
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Stebbings, S.
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Bostan, C.
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Braun, J.
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Kiltz, U., van der Heijde, D., Boonen, A., Cieza, A., Stucki, G., Khan, M.A., Maksymowych, W.P., Marzo-Ortega, H., Reveille, J., Stebbings, S., Bostan, C. and Braun, J. (2014) Development of a health index in patients with ankylosing spondylitis (ASAS HI): final result of a global initiative based on the ICF guided by ASAS. Annals of the Rheumatic Diseases, 74 (5), 830-835. (doi:10.1136/annrheumdis-2013-203967).

Record type: Article

Abstract

Objectives The burden of disease in patients with ankylosing spondylitis (AS) can be considerable. However, no agreement has been reached among expert members of Assessment of SpondyloArthritis International Society (ASAS) to define severity of AS. Based on the International Classification of Functioning, Disability and Health (ICF), a core set of items for AS has been selected to represent the entire spectrum of possible problems in functioning. Based on this, the objective of this study was to develop a tool to quantify health in AS, the ASAS Health Index.

Methods First, based on a literature search, experts’ and patients’ opinion, a large item pool covering the categories of the ICF core set was generated. In several steps this item pool was reduced based on reliability, Rasch analysis and consensus building after two cross-sectional surveys to come up with the best fitting items representing most categories of the ICF core set for AS.

Results After the first survey with 1754 patients, the item pool of 251 items was reduced to 82. After selection by an expert committee, 50 items remained which were tested in a second cross-sectional survey. The results were used to reduce the number of items to a final set of 17 items. This selection showed the best reliability and fit to the Rasch model, no residual correlation, and absence of consistent differential item function and a Person Separation Index of 0.82.

Conclusions In this long sequential study, 17 items which cover most of the ICF core set were identified that showed the best representation of the health status of patients with AS. The ASAS Health Index is a linear composite measure which differs from other measures in the public domain.

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e-pub ahead of print date: 7 January 2014
Published date: 2014
Organisations: Psychology

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Local EPrints ID: 362198
URI: https://eprints.soton.ac.uk/id/eprint/362198
ISSN: 0003-4967
PURE UUID: e6d7248b-7079-448e-9b4c-54b5ac4d0d9a

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Date deposited: 17 Feb 2014 16:41
Last modified: 07 Jun 2018 16:30

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Contributors

Author: U. Kiltz
Author: D. van der Heijde
Author: A. Boonen
Author: A. Cieza
Author: G. Stucki
Author: M.A. Khan
Author: W.P. Maksymowych
Author: H. Marzo-Ortega
Author: J. Reveille
Author: S. Stebbings
Author: C. Bostan
Author: J. Braun

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