Bacterial biofilms and periprosthetic infections
Bacterial biofilms and periprosthetic infections
The diagnosis and treatment of periprosthetic infection after joint arthroplasty is often frustrating for the orthopaedic surgeon. The application of certain diagnostic criteria and different treatment strategies can be better directed if these infections are placed in the context of microbial biofilms. An understanding of this biofilm mode of microbial infection can help to explain the phenomenon of culture-negative infection as well as provide an understanding of why certain treatment modalities often fail. Continued basic research into the role of biofilms in infection will likely provide improved strategies for the clinical diagnosis and treatment of periprosthetic infection.
2223-2229
Arnold, William V
97a31b4b-bd60-4a11-961c-1ee1aeb5c7a6
Shirtliff, Mark E
62549472-d2fa-45c5-9e1c-7d31fe365208
Stoodley, Paul
08614665-92a9-4466-806e-20c6daeb483f
18 December 2013
Arnold, William V
97a31b4b-bd60-4a11-961c-1ee1aeb5c7a6
Shirtliff, Mark E
62549472-d2fa-45c5-9e1c-7d31fe365208
Stoodley, Paul
08614665-92a9-4466-806e-20c6daeb483f
Arnold, William V, Shirtliff, Mark E and Stoodley, Paul
(2013)
Bacterial biofilms and periprosthetic infections.
The Journal of Bone and Joint Surgery, 95 (24), .
(PMID:24498639)
Abstract
The diagnosis and treatment of periprosthetic infection after joint arthroplasty is often frustrating for the orthopaedic surgeon. The application of certain diagnostic criteria and different treatment strategies can be better directed if these infections are placed in the context of microbial biofilms. An understanding of this biofilm mode of microbial infection can help to explain the phenomenon of culture-negative infection as well as provide an understanding of why certain treatment modalities often fail. Continued basic research into the role of biofilms in infection will likely provide improved strategies for the clinical diagnosis and treatment of periprosthetic infection.
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Published date: 18 December 2013
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nCATS Group
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Local EPrints ID: 362368
URI: http://eprints.soton.ac.uk/id/eprint/362368
ISSN: 0021-9355
PURE UUID: 8a5ef7c7-4195-4ec6-b161-e1124b13a98b
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Date deposited: 24 Feb 2014 12:03
Last modified: 28 Apr 2022 02:02
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Author:
William V Arnold
Author:
Mark E Shirtliff
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