Isolation and characterization of 10 MHC Class I-associated microsatellite loci in tammar wallaby (Macropus eugenii)
Isolation and characterization of 10 MHC Class I-associated microsatellite loci in tammar wallaby (Macropus eugenii)
The major histocompatibility complex (MHC) contain genes which play a key role in immune response and mate choice, and are therefore of functional importance to molecular ecologists. Here we describe the design of 10 MHC Class I-associated microsatellite loci from the tammar wallaby. All 10 loci are highly polymorphic, with the expected heterozygosity ranging from 0.547 to 0.919. Six loci successfully cross-amplify in other macropodid species. These microsatellites will serve as useful tools for studying the level of MHC diversity, the impact of selection on genetic variation and the unique structure of the tammar wallaby MHC.
macropodid, marsupial, MHC-associated microsatellite, tammar wallaby
346-349
Cheng, Yuanyuan
5ecff653-5fa6-45f3-ae30-61d4e955f3ac
Wakefield, Matthew
744b5aed-fe3f-4e6a-bf2a-d85fae37b3c1
Siddle, Hannah V.
2f0c1307-55d3-4965-a8b0-495c4a799f27
Coggill, Penny C.
11b5b7c2-d2d3-4ddd-af81-262f2a5307e8
Herbert, Cathy A.
2783effe-1e0c-439c-b29f-32b475c6cd9b
Beck, Stephan
50f0c07a-19a8-4bca-adbc-af41a3800412
Belov, Katherine
53f3bf11-757e-466d-bc93-8958b7a9dae1
Eldridge, Mark D.B.
cbd54e1d-dd36-4108-91ab-bb9f7d770a3a
January 2009
Cheng, Yuanyuan
5ecff653-5fa6-45f3-ae30-61d4e955f3ac
Wakefield, Matthew
744b5aed-fe3f-4e6a-bf2a-d85fae37b3c1
Siddle, Hannah V.
2f0c1307-55d3-4965-a8b0-495c4a799f27
Coggill, Penny C.
11b5b7c2-d2d3-4ddd-af81-262f2a5307e8
Herbert, Cathy A.
2783effe-1e0c-439c-b29f-32b475c6cd9b
Beck, Stephan
50f0c07a-19a8-4bca-adbc-af41a3800412
Belov, Katherine
53f3bf11-757e-466d-bc93-8958b7a9dae1
Eldridge, Mark D.B.
cbd54e1d-dd36-4108-91ab-bb9f7d770a3a
Cheng, Yuanyuan, Wakefield, Matthew, Siddle, Hannah V., Coggill, Penny C., Herbert, Cathy A., Beck, Stephan, Belov, Katherine and Eldridge, Mark D.B.
(2009)
Isolation and characterization of 10 MHC Class I-associated microsatellite loci in tammar wallaby (Macropus eugenii).
Molecular Ecology Resources, 9 (1), .
(doi:10.1111/j.1755-0998.2008.02401.x).
(PMID:21564646)
Abstract
The major histocompatibility complex (MHC) contain genes which play a key role in immune response and mate choice, and are therefore of functional importance to molecular ecologists. Here we describe the design of 10 MHC Class I-associated microsatellite loci from the tammar wallaby. All 10 loci are highly polymorphic, with the expected heterozygosity ranging from 0.547 to 0.919. Six loci successfully cross-amplify in other macropodid species. These microsatellites will serve as useful tools for studying the level of MHC diversity, the impact of selection on genetic variation and the unique structure of the tammar wallaby MHC.
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e-pub ahead of print date: 22 January 2009
Published date: January 2009
Keywords:
macropodid, marsupial, MHC-associated microsatellite, tammar wallaby
Organisations:
Centre for Biological Sciences
Identifiers
Local EPrints ID: 362986
URI: http://eprints.soton.ac.uk/id/eprint/362986
ISSN: 1755-098X
PURE UUID: f741ddc5-d337-4a50-8832-d29407587ae1
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Date deposited: 18 Mar 2014 16:35
Last modified: 15 Mar 2024 03:49
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Contributors
Author:
Yuanyuan Cheng
Author:
Matthew Wakefield
Author:
Penny C. Coggill
Author:
Cathy A. Herbert
Author:
Stephan Beck
Author:
Katherine Belov
Author:
Mark D.B. Eldridge
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