Microfluidic device for compositional analysis of solvent systems at microwave frequencies

Rowe, David J., Porch, Adrian, Barrow, David A. and Allender, Christopher J. (2012) Microfluidic device for compositional analysis of solvent systems at microwave frequencies. Sensors and Actuators B: Chemical, 169, 213-221. (doi:10.1016/j.snb.2012.04.069).

Record type: Article

Abstract

A device for analysing the chemical composition of single- and multi-phase solvent flows using microfluidic dielectric spectroscopy is demonstrated in this work. An open-circuited, half-wavelength, coaxial resonator operating at microwave frequencies (i.e. harmonics of 600 MHz) was embedded in a compression-sealed polytetrafluoroethylene microfluidic chip for in situ characterization of solvent–solvent and solute–solvent mixtures of varying concentration, and an aqueous–organic segmented flow. Results are shown for a solvent mixture of acetonitrile in toluene as a test system, exhibiting a sensitivity limit of 400 nM. In addition to being highly sensitive, the measurement system is fast, robust and non-invasive, and can be readily miniaturized.

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