The University of Southampton
University of Southampton Institutional Repository

Drug-DNA interaction protocols

Drug-DNA interaction protocols
Drug-DNA interaction protocols
The last few years have witnessed the creation of new generations of sequence reading compounds, which have incredible potential for targeting specific DNA sequences. In Drug-DNA Interaction Protocols, Second Edition, expert researchers explore these compounds, revealing how a deeper understanding of the structure of DNA, along with an improved ability to manipulate it, has led to much progress in recent years. Chapters describe a new arsenal of techniques for probing the interactions between drugs and DNA, including various biophysical techniques for quantifying these interactions and for describing them in molecular and atomic detail, and they comprehensively consider both molecular and cellular approaches. Composed in the highly successful Methods in Molecular Biology™ series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls.
biophysical techniques cellular approach, dna-ligand interactions, sequence reading compounds, sequence selectivity, structural approach
978-1-60327-417-3
613
Humana Press
Fox, Keith R.
9da5debc-4e45-473e-ab8c-550d1104659f
Fox, Keith R.
9da5debc-4e45-473e-ab8c-550d1104659f

Fox, Keith R. (ed.) (2010) Drug-DNA interaction protocols (Methods in Molecular Biology, 613), New York, US. Humana Press, 311pp.

Record type: Book

Abstract

The last few years have witnessed the creation of new generations of sequence reading compounds, which have incredible potential for targeting specific DNA sequences. In Drug-DNA Interaction Protocols, Second Edition, expert researchers explore these compounds, revealing how a deeper understanding of the structure of DNA, along with an improved ability to manipulate it, has led to much progress in recent years. Chapters describe a new arsenal of techniques for probing the interactions between drugs and DNA, including various biophysical techniques for quantifying these interactions and for describing them in molecular and atomic detail, and they comprehensively consider both molecular and cellular approaches. Composed in the highly successful Methods in Molecular Biology™ series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls.

Full text not available from this repository.

More information

Published date: 2010
Keywords: biophysical techniques cellular approach, dna-ligand interactions, sequence reading compounds, sequence selectivity, structural approach
Organisations: Centre for Biological Sciences

Identifiers

Local EPrints ID: 364181
URI: https://eprints.soton.ac.uk/id/eprint/364181
ISBN: 978-1-60327-417-3
PURE UUID: 696d7482-2d62-464a-a873-80d3941f4d0c
ORCID for Keith R. Fox: ORCID iD orcid.org/0000-0002-2925-7315

Catalogue record

Date deposited: 08 Apr 2014 12:47
Last modified: 06 Jun 2018 13:16

Export record

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of https://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×