T cells but not NK cells are associated with a favourable outcome for resected colorectal liver metastases
T cells but not NK cells are associated with a favourable outcome for resected colorectal liver metastases
T cells, but not NK cells, are preferentially recruited to colorectal liver metastases. NK cells within colorectal metastases have an intrahepatic and potentially tolerogenic, rather than a peripheral, phenotype. Similar to primary tumours, the magnitude of the T cell infiltrate in colorectal metastases is positively associated with survival
180
Pugh, Siân A
83010563-0865-446c-ba71-95e2a45d9562
Harrison, Rebecca J.
848aa9dc-797f-40f8-b63d-bca0d90f7b55
Primrose, John N.
d85f3b28-24c6-475f-955b-ec457a3f9185
Khakoo, Salim I.
6c16d2f5-ae80-4d9b-9100-6bfb34ad0273
2014
Pugh, Siân A
83010563-0865-446c-ba71-95e2a45d9562
Harrison, Rebecca J.
848aa9dc-797f-40f8-b63d-bca0d90f7b55
Primrose, John N.
d85f3b28-24c6-475f-955b-ec457a3f9185
Khakoo, Salim I.
6c16d2f5-ae80-4d9b-9100-6bfb34ad0273
Pugh, Siân A, Harrison, Rebecca J., Primrose, John N. and Khakoo, Salim I.
(2014)
T cells but not NK cells are associated with a favourable outcome for resected colorectal liver metastases.
BMC cancer, 14, .
(doi:10.1186/1471-2407-14-180).
(PMID:24625075)
Abstract
T cells, but not NK cells, are preferentially recruited to colorectal liver metastases. NK cells within colorectal metastases have an intrahepatic and potentially tolerogenic, rather than a peripheral, phenotype. Similar to primary tumours, the magnitude of the T cell infiltrate in colorectal metastases is positively associated with survival
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Published date: 2014
Organisations:
Cancer Sciences
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Local EPrints ID: 364217
URI: http://eprints.soton.ac.uk/id/eprint/364217
ISSN: 1471-2407
PURE UUID: 15c56f64-7321-4b64-8b65-63ae20791007
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Date deposited: 10 Apr 2014 08:54
Last modified: 15 Mar 2024 03:12
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Author:
Siân A Pugh
Author:
Rebecca J. Harrison
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