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Effects of prolonged exposure to hypobaric hypoxia on oxidative stress, inflammation and gluco-insular regulation: the not-so-sweet price for good regulation.

Record type: Article

Sustained hypoxemia is associated with insulin resistance, whose magnitude correlates with the degree of oxidative stress and inflammation. The role of 4-HNE and IL-6 as key players in modifying the association between sustained hypoxia and insulin resistance merits further investigation.

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Citation

Siervo, Mario, Riley, Heather L., Fernandez, Bernadette O, Leckstrom, Carl A., Martin, Daniel S., Mitchell, Kay, Levett, Denny Z.H., Montgomery, Hugh E., Mythen, Monty G., Grocott, Michael P. W. and Feelisch, Martin (2014) Effects of prolonged exposure to hypobaric hypoxia on oxidative stress, inflammation and gluco-insular regulation: the not-so-sweet price for good regulation. PLoS ONE, 9, (4), e94915. (doi:10.1371/journal.pone.0094915). (PMID:15134560).

More information

Published date: 2014
Organisations: Clinical & Experimental Sciences

Identifiers

Local EPrints ID: 364357
URI: http://eprints.soton.ac.uk/id/eprint/364357
ISSN: 1932-6203
PURE UUID: f6d03e0a-0b56-40cd-a36b-53461709d7b0
ORCID for Martin Feelisch: ORCID iD orcid.org/0000-0003-2320-1158

Catalogue record

Date deposited: 24 Apr 2014 14:24
Last modified: 18 Jul 2017 02:32

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Contributors

Author: Mario Siervo
Author: Heather L. Riley
Author: Bernadette O Fernandez
Author: Carl A. Leckstrom
Author: Daniel S. Martin
Author: Kay Mitchell
Author: Denny Z.H. Levett
Author: Hugh E. Montgomery
Author: Monty G. Mythen
Author: Martin Feelisch ORCID iD

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