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Determinants of nocturnal enuresis in homozygous sickle cell disease

Determinants of nocturnal enuresis in homozygous sickle cell disease
Determinants of nocturnal enuresis in homozygous sickle cell disease
The determinants of nocturnal enuresis in homozygous sickle cell (SS) disease have been investigated in 16 enuretic and 16 age and sex matched non-enuretic children. Overnight fluid deprivation tests (8pm-8am) demonstrated no significant difference in maximum urine osmolality or urine volumes, although the latter tended to be higher in the enuretic children. Maximum functional bladder capacity, estimated by maximum voided volume during oral fluid loading, was lower and the ratio of overnight urine volume to maximum functional bladder capacity higher in the enuretic than the non-enuretic group. Enuretic children were more likely than non-enuretics to be considered deep sleepers by their family. High urine volumes may contribute to nocturnal enuresis in SS disease, although the similar values in enuretic and non-enuretic children implies that additional factors determine the presence of enuresis. Low maximum functional bladder capacity, and a high ratio of overnight urine volume to maximum functional bladder capacity, appear to be important determinants
0003-9888
615-618
Readett, D.R.J.
a6c4591a-4387-4d49-9f38-4eb895510223
Morris, J.S.
569aa43b-15bd-4e9d-b4a5-e68a84334cfe
Serjeant, G.R.
0ee3a15b-b982-4b24-adbf-c1b0ebb65b71
Readett, D.R.J.
a6c4591a-4387-4d49-9f38-4eb895510223
Morris, J.S.
569aa43b-15bd-4e9d-b4a5-e68a84334cfe
Serjeant, G.R.
0ee3a15b-b982-4b24-adbf-c1b0ebb65b71

Readett, D.R.J., Morris, J.S. and Serjeant, G.R. (1990) Determinants of nocturnal enuresis in homozygous sickle cell disease. Archives of Disease in Childhood, 65, 615-618. (doi:10.1136/adc.65.6.615).

Record type: Article

Abstract

The determinants of nocturnal enuresis in homozygous sickle cell (SS) disease have been investigated in 16 enuretic and 16 age and sex matched non-enuretic children. Overnight fluid deprivation tests (8pm-8am) demonstrated no significant difference in maximum urine osmolality or urine volumes, although the latter tended to be higher in the enuretic children. Maximum functional bladder capacity, estimated by maximum voided volume during oral fluid loading, was lower and the ratio of overnight urine volume to maximum functional bladder capacity higher in the enuretic than the non-enuretic group. Enuretic children were more likely than non-enuretics to be considered deep sleepers by their family. High urine volumes may contribute to nocturnal enuresis in SS disease, although the similar values in enuretic and non-enuretic children implies that additional factors determine the presence of enuresis. Low maximum functional bladder capacity, and a high ratio of overnight urine volume to maximum functional bladder capacity, appear to be important determinants

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Published date: 1990
Organisations: Faculty of Health Sciences

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Local EPrints ID: 365098
URI: https://eprints.soton.ac.uk/id/eprint/365098
ISSN: 0003-9888
PURE UUID: 564227ff-dcad-4913-95a9-106c47867995

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Date deposited: 27 May 2014 09:01
Last modified: 23 Apr 2018 16:32

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