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Risk factors for HTLV-1 among heterosexual STD clinic attenders

Risk factors for HTLV-1 among heterosexual STD clinic attenders
Risk factors for HTLV-1 among heterosexual STD clinic attenders
Summary: Human T-cell lymphotropic virus type 1 (HTLV-I) status was assessed in 994 patients attending a sexually transmitted disease (STD) clinic in Kingston, Jamaica, between November 1990 and January 1991 for a new STD complaint. Of 515 heterosexual men, 36 (7.0%) were HTLV-I seropositive, as were 38 (7.9%) of 479 women. HTLV-I seroprevalence increased with age in women. A history of blood transfusion was associated with HTLV-I in both sexes, significantly so in men [odds ratio (OR) 4.7, confidence interval (CI) 1.1-1.7 for men; OR 1.9, CI 0.6-5.0 for women]. Further analysis excluded all persons reporting a transfusion. On multiple logistic regression analysis, independent associations with HTLV-I infection in men were shown for marital status (OR 3.5, CI 1.2-1.0 for married/common law vs. single/visiting unions), agricultural occupation (OR 9.0, CI 2.0-41), bruising during sex (OR 2.9, CI 1.0-8.1),> 15 years at first sexual intercourse (OR 2.9, CI 1.0-8.2), and a positive test for hepatitis B surface antigen (OR 7.3, CI 1.2-52). In women, associations were shown for two or more sex partners in the 4 weeks prior to complaint (OR 4.9, CI 1.8-13), 11 or more lifetime sexual partners (OR 5.9, CI 1.3-27), aged <15 years at first sexual intercourse (OR 2.3, 1.0-5.4), bruising during sex (OR 2.7, CI 1.1-6.6), microhaemagglutination-Treponema pallidum positivity (OR 3.6, CI 1.6-8.4), and human immunodeficiency virus infection (OR 1.4, CI 2.1-9.2). STDs and bruising during sex may facilitate sexual trans-mission of HTLV-I, whereas sexual activity is a more important risk factor in women than men. Programs promoting safer sexual practices and controlling STDs may reduce HTLV-1 infection in Jamaica.
1077-9450
81-88
Figueroa, J.P.
98aaa99a-173b-4bba-be78-b5ea46d85bb2
Morris, J.S.
569aa43b-15bd-4e9d-b4a5-e68a84334cfe
Braithwaite, A.
dfaff376-dcbc-4d24-831f-4052257c4a49
Ward, E.
92107261-5906-4e12-8868-a771661650a3
Peruga, A.
7e344756-6817-427d-bee5-05365a0d52b9
Hayes, R.
1e72f202-76cd-4bad-ac5a-570925e9004e
Vermund, S.H.
17268028-ec9b-4db3-b546-411084469440
Blattner, W.
38afd3d3-d633-4a9d-af01-7c242f910897
Figueroa, J.P.
98aaa99a-173b-4bba-be78-b5ea46d85bb2
Morris, J.S.
569aa43b-15bd-4e9d-b4a5-e68a84334cfe
Braithwaite, A.
dfaff376-dcbc-4d24-831f-4052257c4a49
Ward, E.
92107261-5906-4e12-8868-a771661650a3
Peruga, A.
7e344756-6817-427d-bee5-05365a0d52b9
Hayes, R.
1e72f202-76cd-4bad-ac5a-570925e9004e
Vermund, S.H.
17268028-ec9b-4db3-b546-411084469440
Blattner, W.
38afd3d3-d633-4a9d-af01-7c242f910897

Figueroa, J.P., Morris, J.S., Braithwaite, A., Ward, E., Peruga, A., Hayes, R., Vermund, S.H. and Blattner, W. (1995) Risk factors for HTLV-1 among heterosexual STD clinic attenders. Journal of Acquired Immune Deficiency Syndromes & Human Retrovirology, 9 (1), 81-88.

Record type: Article

Abstract

Summary: Human T-cell lymphotropic virus type 1 (HTLV-I) status was assessed in 994 patients attending a sexually transmitted disease (STD) clinic in Kingston, Jamaica, between November 1990 and January 1991 for a new STD complaint. Of 515 heterosexual men, 36 (7.0%) were HTLV-I seropositive, as were 38 (7.9%) of 479 women. HTLV-I seroprevalence increased with age in women. A history of blood transfusion was associated with HTLV-I in both sexes, significantly so in men [odds ratio (OR) 4.7, confidence interval (CI) 1.1-1.7 for men; OR 1.9, CI 0.6-5.0 for women]. Further analysis excluded all persons reporting a transfusion. On multiple logistic regression analysis, independent associations with HTLV-I infection in men were shown for marital status (OR 3.5, CI 1.2-1.0 for married/common law vs. single/visiting unions), agricultural occupation (OR 9.0, CI 2.0-41), bruising during sex (OR 2.9, CI 1.0-8.1),> 15 years at first sexual intercourse (OR 2.9, CI 1.0-8.2), and a positive test for hepatitis B surface antigen (OR 7.3, CI 1.2-52). In women, associations were shown for two or more sex partners in the 4 weeks prior to complaint (OR 4.9, CI 1.8-13), 11 or more lifetime sexual partners (OR 5.9, CI 1.3-27), aged <15 years at first sexual intercourse (OR 2.3, 1.0-5.4), bruising during sex (OR 2.7, CI 1.1-6.6), microhaemagglutination-Treponema pallidum positivity (OR 3.6, CI 1.6-8.4), and human immunodeficiency virus infection (OR 1.4, CI 2.1-9.2). STDs and bruising during sex may facilitate sexual trans-mission of HTLV-I, whereas sexual activity is a more important risk factor in women than men. Programs promoting safer sexual practices and controlling STDs may reduce HTLV-1 infection in Jamaica.

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Published date: May 1995
Organisations: Faculty of Health Sciences

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Local EPrints ID: 365379
URI: http://eprints.soton.ac.uk/id/eprint/365379
ISSN: 1077-9450
PURE UUID: cea4057a-bc21-4153-b0b3-b102551b5cd2

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Date deposited: 03 Jun 2014 13:50
Last modified: 10 Jul 2020 16:32

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Contributors

Author: J.P. Figueroa
Author: J.S. Morris
Author: A. Braithwaite
Author: E. Ward
Author: A. Peruga
Author: R. Hayes
Author: S.H. Vermund
Author: W. Blattner

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