Letter. Intensity-modulated radiotherapy for the treatment of breast cancer
Letter. Intensity-modulated radiotherapy for the treatment of breast cancer
In the systematic review of intensity-modulated radiotherapy (IMRT) in the treatment of breast cancer reported in Clinical Oncology by Dayes and colleagues [1], the only prospective randomised clinical trial (n = 306) testing forward-planned IMRT to have reported a 5 year outcome for adverse effects [2] was excluded on the spurious grounds that no outcomes of interest were reported (Appendix 3). In this trial, the control arm patients were 1.7 times more likely to have a change in breast appearance than the IMRT arm patients after adjustment for the year of photographic assessment (95% confidence interval 1.2–2.5, P = 0.008).
215-215
Coles, C.E.
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Donovan, E.
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Haviland, J.S.
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Yarnold, J.
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March 2013
Coles, C.E.
627dfe0d-3876-4fcf-8e70-431e3649e257
Donovan, E.
f10e198f-0476-4a3f-87a8-46335881db20
Haviland, J.S.
569aa43b-15bd-4e9d-b4a5-e68a84334cfe
Yarnold, J.
0003b4fd-a371-4258-890f-ffd3d0b5c3a9
Coles, C.E., Donovan, E., Haviland, J.S. and Yarnold, J.
(2013)
Letter. Intensity-modulated radiotherapy for the treatment of breast cancer.
Clinical Oncology, 25 (3), .
(doi:10.1016/j.clon.2012.11.003).
Abstract
In the systematic review of intensity-modulated radiotherapy (IMRT) in the treatment of breast cancer reported in Clinical Oncology by Dayes and colleagues [1], the only prospective randomised clinical trial (n = 306) testing forward-planned IMRT to have reported a 5 year outcome for adverse effects [2] was excluded on the spurious grounds that no outcomes of interest were reported (Appendix 3). In this trial, the control arm patients were 1.7 times more likely to have a change in breast appearance than the IMRT arm patients after adjustment for the year of photographic assessment (95% confidence interval 1.2–2.5, P = 0.008).
Text
IMRT letter Clin Onc 2013.pdf
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e-pub ahead of print date: 3 December 2012
Published date: March 2013
Organisations:
Faculty of Health Sciences
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Local EPrints ID: 365654
URI: http://eprints.soton.ac.uk/id/eprint/365654
ISSN: 0936-6555
PURE UUID: 5035f0fb-8e3e-4a0b-bbe6-7a4dfab0eb00
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Date deposited: 16 Jun 2014 09:33
Last modified: 14 Mar 2024 16:59
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Author:
C.E. Coles
Author:
E. Donovan
Author:
J.S. Haviland
Author:
J. Yarnold
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