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A controlled neuropsycholgical study of HIV-seropositive and HIV-seronegative adolescent haemophiliacs

A controlled neuropsycholgical study of HIV-seropositive and HIV-seronegative adolescent haemophiliacs
A controlled neuropsycholgical study of HIV-seropositive and HIV-seronegative adolescent haemophiliacs
Sixty-four males with haemophilia were assessed with a series of neuropsychological tests and a structured interview for psychiatric symptoms. Thirty-one had been infected with human immunodeficiency virus (HIV) before the age of 18 and were in various stages of the disease at the time of testing and 33 were HIV negative. Sixteen male control subjects were recruited to match in age with the haemophilia group. The HIV-seropositive group were older than the HIV-negative group due to the cohort effect of the time of infection. Contrary to predictions from the known effects of HIV on the central nervous system the HIV-seropositive group performed better on many of the tests than the HIV-seronegative group. In some but not all of the tests this may have been an age effect. There was very little psychiatric morbidity, consistent with the view that high levels of psychological support provided by the haemophilia units can alleviate the effects of the illness on emotions and behaviour. These findings form a baseline for a 2-year follow-up study which is in progress
1351-8216
145-152
Thompson, C.
10784aa4-0fd2-42d4-8c1d-db11eb86e5a2
Westwell, P.
264962b0-4188-4c77-92d0-2b553d662e50
Viney, D.
5e392387-eb1e-4ae8-929b-904593be6d14
Wilson, B.A.
c4819bd4-0b13-42eb-92c7-7812f01b013a
Hill, F.
c6e1384d-7f48-4654-863f-8ac754cd2c15
Harrington, R.
66664b1f-c801-42a2-835b-bee222cbba7d
Bryant, T.N.
ef0188d5-2df5-432d-b5be-a3bc2a6123b2
Pickering, R.
4a828314-7ddf-4f96-abed-3407017d4c90
Thompson, C.
10784aa4-0fd2-42d4-8c1d-db11eb86e5a2
Westwell, P.
264962b0-4188-4c77-92d0-2b553d662e50
Viney, D.
5e392387-eb1e-4ae8-929b-904593be6d14
Wilson, B.A.
c4819bd4-0b13-42eb-92c7-7812f01b013a
Hill, F.
c6e1384d-7f48-4654-863f-8ac754cd2c15
Harrington, R.
66664b1f-c801-42a2-835b-bee222cbba7d
Bryant, T.N.
ef0188d5-2df5-432d-b5be-a3bc2a6123b2
Pickering, R.
4a828314-7ddf-4f96-abed-3407017d4c90

Thompson, C., Westwell, P., Viney, D., Wilson, B.A., Hill, F., Harrington, R., Bryant, T.N. and Pickering, R. (1996) A controlled neuropsycholgical study of HIV-seropositive and HIV-seronegative adolescent haemophiliacs. Haemophilia, 2 (3), 145-152. (doi:10.1111/j.1365-2516.1996.tb00158.x).

Record type: Article

Abstract

Sixty-four males with haemophilia were assessed with a series of neuropsychological tests and a structured interview for psychiatric symptoms. Thirty-one had been infected with human immunodeficiency virus (HIV) before the age of 18 and were in various stages of the disease at the time of testing and 33 were HIV negative. Sixteen male control subjects were recruited to match in age with the haemophilia group. The HIV-seropositive group were older than the HIV-negative group due to the cohort effect of the time of infection. Contrary to predictions from the known effects of HIV on the central nervous system the HIV-seropositive group performed better on many of the tests than the HIV-seronegative group. In some but not all of the tests this may have been an age effect. There was very little psychiatric morbidity, consistent with the view that high levels of psychological support provided by the haemophilia units can alleviate the effects of the illness on emotions and behaviour. These findings form a baseline for a 2-year follow-up study which is in progress

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Published date: 1996
Organisations: Primary Care & Population Sciences

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Local EPrints ID: 365950
URI: https://eprints.soton.ac.uk/id/eprint/365950
ISSN: 1351-8216
PURE UUID: e7ab3d58-2a0a-4ab2-9b0d-cc7d04972887

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Date deposited: 20 Jun 2014 08:32
Last modified: 18 Jul 2017 02:17

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