The University of Southampton
University of Southampton Institutional Repository

Mid-infrared Ta2O5 waveguides for evanescent sensing of stem cell differentiation

Mid-infrared Ta2O5 waveguides for evanescent sensing of stem cell differentiation
Mid-infrared Ta2O5 waveguides for evanescent sensing of stem cell differentiation
Stem cell differentiation is a fundamental biological process of particular interest for regenerative medicine. Differentiated cells have been characterised using mid-infrared FTIR microscopy but the use of spatially unresolved spectroscopy remains unexplored. Evanescent waveguide sensing may allow non-contact, label-free and real-time monitoring of differentiation. We report preliminary FTIR-ATR measurements which successfully distinguish between lysates of cells grown under different conditions and initial results on the fabrication of mid-infrared Ta2O5 waveguides. We also identify potential routes to a wholly self-contained analytical device.
Rowe, D.J.
a0e0fe82-5e29-42b8-b370-5236a722f015
Evans, N.D.
06a05c97-bfed-4abb-9244-34ec9f4b4b95
Murugan, G.S.
a867686e-0535-46cc-ad85-c2342086b25b
Pearce, S.J.
1d0ee7c5-8f72-4783-a034-9b2f67de3531
Wilkinson, J.S.
73483cf3-d9f2-4688-9b09-1c84257884ca
Rowe, D.J.
a0e0fe82-5e29-42b8-b370-5236a722f015
Evans, N.D.
06a05c97-bfed-4abb-9244-34ec9f4b4b95
Murugan, G.S.
a867686e-0535-46cc-ad85-c2342086b25b
Pearce, S.J.
1d0ee7c5-8f72-4783-a034-9b2f67de3531
Wilkinson, J.S.
73483cf3-d9f2-4688-9b09-1c84257884ca

Rowe, D.J., Evans, N.D., Murugan, G.S., Pearce, S.J. and Wilkinson, J.S. (2014) Mid-infrared Ta2O5 waveguides for evanescent sensing of stem cell differentiation. 17th European Conference on Integrated Optics, 19th MicroOptics Conference, France. 24 - 27 Jun 2014. 2 pp .

Record type: Conference or Workshop Item (Paper)

Abstract

Stem cell differentiation is a fundamental biological process of particular interest for regenerative medicine. Differentiated cells have been characterised using mid-infrared FTIR microscopy but the use of spatially unresolved spectroscopy remains unexplored. Evanescent waveguide sensing may allow non-contact, label-free and real-time monitoring of differentiation. We report preliminary FTIR-ATR measurements which successfully distinguish between lysates of cells grown under different conditions and initial results on the fabrication of mid-infrared Ta2O5 waveguides. We also identify potential routes to a wholly self-contained analytical device.

Text
6492.pdf - Other
Download (195kB)

More information

e-pub ahead of print date: 2014
Venue - Dates: 17th European Conference on Integrated Optics, 19th MicroOptics Conference, France, 2014-06-24 - 2014-06-27
Organisations: Optoelectronics Research Centre, Human Development & Health

Identifiers

Local EPrints ID: 366302
URI: http://eprints.soton.ac.uk/id/eprint/366302
PURE UUID: ee7ce137-181b-4557-a76a-a03b1d363af8
ORCID for D.J. Rowe: ORCID iD orcid.org/0000-0002-1167-150X
ORCID for G.S. Murugan: ORCID iD orcid.org/0000-0002-2733-3273
ORCID for J.S. Wilkinson: ORCID iD orcid.org/0000-0003-4712-1697

Catalogue record

Date deposited: 23 Jul 2014 16:56
Last modified: 18 Feb 2021 17:20

Export record

Contributors

Author: D.J. Rowe ORCID iD
Author: N.D. Evans
Author: G.S. Murugan ORCID iD
Author: S.J. Pearce
Author: J.S. Wilkinson ORCID iD

University divisions

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×