Trier social stress test in Indian adolescents
Trier social stress test in Indian adolescents
Objective: To test the Trier Social Stress Test for children (TSST-C) in a cohort of Indian adolescents.
Design: Cohort study.
Setting: Holdsworth Memorial Hospital, Mysore, India.
Participants: Adolescent children (N=273, 134 males; mean age 13.6 yrs) selected from an ongoing birth cohort; 269 completed the test.
Intervention: Performance of 5-minutes each of public- speaking and mental arithmetic tasks in front of two unfamiliar 'evaluators'.
Outcome Measures: Salivary cortisol concentrations were measured at baseline and at regular intervals after the TSST-C. Continuous measurements of heart rate, finger blood pressure, stroke volume, cardiac output and systemic vascular resistance were carried out before, during and for 10 minutes after the TSST-C using a finger cuff.
Results: Cortisol concentrations [mean increment (SD): 6.1 (6.9) ng/mL], heart rate [4.6 (10.1) bpm], systolic [24.2 (11.6) mmHg] and diastolic blood pressure [16.5 (7.3) mmHg], cardiac output [0.6 (0.7) L/min], stroke volume [4.0 (5.6) mL] and systemic vascular resistance [225 (282) dyn.s/cm5] increased significantly (P<0.001) from baseline after inducing stress.
Conclusions:The TSST-C produces stress responses in Indian adolescents of a sufficient magnitude to be a useful tool for examining stress physiology and its relationships to disease outcomes in this population
463-467
Krishnaveni, G.V.
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Veena, S.R.
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Jones, A.
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Bhat, D.S.
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Malathi, M.P.
088873b7-54f3-458c-8e48-db08827564e9
Hellhammer, D.
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Srinivasan, K.
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Upadya, H.
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Kurpad, A.V.
35ccfb0b-44b2-4dfc-969c-15160007f9c6
Fall, C.H.
7171a105-34f5-4131-89d7-1aa639893b18
8 June 2014
Krishnaveni, G.V.
e9cc468a-8262-4dde-8eba-e047c68a3dce
Veena, S.R.
2acd1a9f-ce06-4cd2-bbdb-8f0057308e0e
Jones, A.
bcae84a4-4191-4a3e-b695-1b6e2b0681c7
Bhat, D.S.
75412cda-4b68-4286-82e2-8f9ea39fd842
Malathi, M.P.
088873b7-54f3-458c-8e48-db08827564e9
Hellhammer, D.
6dfb54e6-10dc-47f3-8dee-e2b4d76072cc
Srinivasan, K.
a5367aa3-c40e-4c3c-825e-2d150a3e40c5
Upadya, H.
1d110682-b14e-4f5d-85d0-dddcb4d91eb8
Kurpad, A.V.
35ccfb0b-44b2-4dfc-969c-15160007f9c6
Fall, C.H.
7171a105-34f5-4131-89d7-1aa639893b18
Krishnaveni, G.V., Veena, S.R., Jones, A., Bhat, D.S., Malathi, M.P., Hellhammer, D., Srinivasan, K., Upadya, H., Kurpad, A.V. and Fall, C.H.
(2014)
Trier social stress test in Indian adolescents.
Indian pediatrics, 51 (6), .
(PMID:24986282)
Abstract
Objective: To test the Trier Social Stress Test for children (TSST-C) in a cohort of Indian adolescents.
Design: Cohort study.
Setting: Holdsworth Memorial Hospital, Mysore, India.
Participants: Adolescent children (N=273, 134 males; mean age 13.6 yrs) selected from an ongoing birth cohort; 269 completed the test.
Intervention: Performance of 5-minutes each of public- speaking and mental arithmetic tasks in front of two unfamiliar 'evaluators'.
Outcome Measures: Salivary cortisol concentrations were measured at baseline and at regular intervals after the TSST-C. Continuous measurements of heart rate, finger blood pressure, stroke volume, cardiac output and systemic vascular resistance were carried out before, during and for 10 minutes after the TSST-C using a finger cuff.
Results: Cortisol concentrations [mean increment (SD): 6.1 (6.9) ng/mL], heart rate [4.6 (10.1) bpm], systolic [24.2 (11.6) mmHg] and diastolic blood pressure [16.5 (7.3) mmHg], cardiac output [0.6 (0.7) L/min], stroke volume [4.0 (5.6) mL] and systemic vascular resistance [225 (282) dyn.s/cm5] increased significantly (P<0.001) from baseline after inducing stress.
Conclusions:The TSST-C produces stress responses in Indian adolescents of a sufficient magnitude to be a useful tool for examining stress physiology and its relationships to disease outcomes in this population
Text
Krishnaveni_TSST-C_methods paper_Final_submission.doc
- Accepted Manuscript
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Krishnaveni et al_Fig 1.doc
- Accepted Manuscript
Text
Krishnaveni et al_Fig 2.doc
- Accepted Manuscript
More information
Published date: 8 June 2014
Organisations:
Faculty of Medicine
Identifiers
Local EPrints ID: 367228
URI: http://eprints.soton.ac.uk/id/eprint/367228
ISSN: 0019-6061
PURE UUID: f0323c62-45f6-4ed4-9477-85d26ff66084
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Date deposited: 19 Aug 2014 10:28
Last modified: 15 Mar 2024 02:40
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Contributors
Author:
G.V. Krishnaveni
Author:
S.R. Veena
Author:
A. Jones
Author:
D.S. Bhat
Author:
M.P. Malathi
Author:
D. Hellhammer
Author:
K. Srinivasan
Author:
H. Upadya
Author:
A.V. Kurpad
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