Tissue motion annular displacement of the mitral valve using two-dimensional speckle tracking echocardiology predicts the left ventricular ejection fraction in normal children
Tissue motion annular displacement of the mitral valve using two-dimensional speckle tracking echocardiology predicts the left ventricular ejection fraction in normal children
BACKGROUND: The gold standard for determining the left ventricular ejection fraction is cardiac magnetic resonance imaging. Other parameters for determining the ejection fraction such as M-mode echocardiography are operator-dependant and often inaccurate. Assessment of the displacement of the mitral valve annulus using two-dimensional speckle tracking echocardiography may provide an accurate and simple method of determining the left ventricular ejection fraction in children.
METHOD: We retrospectively studied 70 healthy 9-year-old children with no history of cardiovascular disease who had been assessed using cardiac magnetic resonance imaging and two-dimensional transthoracic echocardiography. Mitral displacement was determined using the tissue motion annular displacement (TMAD) feature of Philips QLAB version 9. The midpoint displacement of the mitral valve was calculated, and the predicted left ventricular ejection fraction was compared with magnetic resonance imaging-derived and M-mode-derived ejection fractions.
RESULTS: The mean ejection fraction derived from magnetic resonance imaging (64.5 (4.6)) was similar to that derived from the TMAD midpoint (60.9 (2.7), p = 0.001) and the M-mode (61.9 (7), p = 0.012). The TMAD midpoint correlated strongly with the magnetic resonance imaging-derived ejection fraction (r = 0.69, p < 0.001), as did the predicted fraction (r = 0.67, p < 0.001). The M-mode ejection fraction showed a poor linear correlation with both magnetic resonance imaging-derived and TMAD-derived fractions (r = 0.33 and 0.04, respectively).
CONCLUSION: TMAD of the mitral valve is a simple, effective, and highly reproducible method of assessing the ejection fraction in normal children. It shows a strong linear correlation with magnetic resonance imaging-derived ejection fraction and is superior to M-mode-derived ejection fractions.
speckle tracking, mitral displacement, function
640-648
Black, D.E.
77ab5612-d40a-45c2-b88a-f55f1d1ec91a
Bryant, J.
508f497c-8b5a-468f-a37d-be9c26e4e49d
Peebles, Charles R.
8eb51995-0f07-46f7-9ca2-f97301fefc3d
Godfrey, Keith M.
0931701e-fe2c-44b5-8f0d-ec5c7477a6fd
Hanson, Mark A.
1952fad1-abc7-4284-a0bc-a7eb31f70a3f
Vettukattil, Joseph J.
6733316f-b576-4864-b41f-5da015f78887
August 2014
Black, D.E.
77ab5612-d40a-45c2-b88a-f55f1d1ec91a
Bryant, J.
508f497c-8b5a-468f-a37d-be9c26e4e49d
Peebles, Charles R.
8eb51995-0f07-46f7-9ca2-f97301fefc3d
Godfrey, Keith M.
0931701e-fe2c-44b5-8f0d-ec5c7477a6fd
Hanson, Mark A.
1952fad1-abc7-4284-a0bc-a7eb31f70a3f
Vettukattil, Joseph J.
6733316f-b576-4864-b41f-5da015f78887
Black, D.E., Bryant, J., Peebles, Charles R., Godfrey, Keith M., Hanson, Mark A. and Vettukattil, Joseph J.
(2014)
Tissue motion annular displacement of the mitral valve using two-dimensional speckle tracking echocardiology predicts the left ventricular ejection fraction in normal children.
Cardiology in the Young, 24 (4), .
(doi:10.1017/S1047951113000863).
(PMID:23803408)
Abstract
BACKGROUND: The gold standard for determining the left ventricular ejection fraction is cardiac magnetic resonance imaging. Other parameters for determining the ejection fraction such as M-mode echocardiography are operator-dependant and often inaccurate. Assessment of the displacement of the mitral valve annulus using two-dimensional speckle tracking echocardiography may provide an accurate and simple method of determining the left ventricular ejection fraction in children.
METHOD: We retrospectively studied 70 healthy 9-year-old children with no history of cardiovascular disease who had been assessed using cardiac magnetic resonance imaging and two-dimensional transthoracic echocardiography. Mitral displacement was determined using the tissue motion annular displacement (TMAD) feature of Philips QLAB version 9. The midpoint displacement of the mitral valve was calculated, and the predicted left ventricular ejection fraction was compared with magnetic resonance imaging-derived and M-mode-derived ejection fractions.
RESULTS: The mean ejection fraction derived from magnetic resonance imaging (64.5 (4.6)) was similar to that derived from the TMAD midpoint (60.9 (2.7), p = 0.001) and the M-mode (61.9 (7), p = 0.012). The TMAD midpoint correlated strongly with the magnetic resonance imaging-derived ejection fraction (r = 0.69, p < 0.001), as did the predicted fraction (r = 0.67, p < 0.001). The M-mode ejection fraction showed a poor linear correlation with both magnetic resonance imaging-derived and TMAD-derived fractions (r = 0.33 and 0.04, respectively).
CONCLUSION: TMAD of the mitral valve is a simple, effective, and highly reproducible method of assessing the ejection fraction in normal children. It shows a strong linear correlation with magnetic resonance imaging-derived ejection fraction and is superior to M-mode-derived ejection fractions.
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e-pub ahead of print date: 27 June 2013
Published date: August 2014
Keywords:
speckle tracking, mitral displacement, function
Organisations:
Human Development & Health
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Local EPrints ID: 367306
URI: http://eprints.soton.ac.uk/id/eprint/367306
ISSN: 1047-9511
PURE UUID: 8ea8cffd-bf9b-4423-a5f3-d477a0d2119a
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Date deposited: 26 Aug 2014 10:28
Last modified: 15 Mar 2024 03:07
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Author:
D.E. Black
Author:
J. Bryant
Author:
Charles R. Peebles
Author:
Joseph J. Vettukattil
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