Gestational diabetes, maternal obesity and the NCD burden
Gestational diabetes, maternal obesity and the NCD burden
A greater proportion of women of reproductive age are now overweight or obese. Gestational diabetes mellitus and maternal obesity are associated with long-term adverse consequences in the offspring and subsequent generations, and are important drivers of the escalating global burden of diabetes and cardiovascular disease. We review the evidence linking gestational diabetes mellitus and maternal obesity with a greater risk of metabolic compromise in the offspring. We use an evolutionary perspective to elucidate the origins of gestational diabetes. Focusing efforts on maternal health is an important approach to combating the growing burden of diabetes and other noncommunicable diseases.
633-641
Ma, R.
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Chan, J.
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Tam, W.
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Hanson, Mark A.
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Gluckman, P.
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September 2013
Ma, R.
ad0ef11f-e957-40bc-8426-fca0171ac862
Chan, J.
7c9ec89b-38f8-4209-9b2f-a067d54621c1
Tam, W.
e11d8a96-9cb6-41c2-ad6a-543b6d91ba3d
Hanson, Mark A.
1952fad1-abc7-4284-a0bc-a7eb31f70a3f
Gluckman, P.
dadc86d4-4eaa-4589-b560-413a9e564558
Ma, R., Chan, J., Tam, W., Hanson, Mark A. and Gluckman, P.
(2013)
Gestational diabetes, maternal obesity and the NCD burden.
Clinical Obstetrics & Gynecology, 56 (3), .
(doi:10.1097/GRF.0b013e31829e5bb0).
(PMID:23820121)
Abstract
A greater proportion of women of reproductive age are now overweight or obese. Gestational diabetes mellitus and maternal obesity are associated with long-term adverse consequences in the offspring and subsequent generations, and are important drivers of the escalating global burden of diabetes and cardiovascular disease. We review the evidence linking gestational diabetes mellitus and maternal obesity with a greater risk of metabolic compromise in the offspring. We use an evolutionary perspective to elucidate the origins of gestational diabetes. Focusing efforts on maternal health is an important approach to combating the growing burden of diabetes and other noncommunicable diseases.
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Published date: September 2013
Organisations:
Human Development & Health
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Local EPrints ID: 367320
URI: http://eprints.soton.ac.uk/id/eprint/367320
ISSN: 0009-9201
PURE UUID: b5e14047-f632-4b87-a5a5-9d4eae6a901a
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Date deposited: 26 Aug 2014 11:28
Last modified: 15 Mar 2024 03:07
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Author:
R. Ma
Author:
J. Chan
Author:
W. Tam
Author:
P. Gluckman
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