The challenges of genome analysis in the health care setting
The challenges of genome analysis in the health care setting
Genome sequencing is now a sufficiently mature and affordable technology for clinical use. Its application promises not only to transform clinicians' diagnostic and predictive ability, but also to improve preventative therapies, surveillance regimes, and tailor patient treatment to an individual's genetic make-up. However, as with any technological advance, there are associated fresh challenges. While some of the ethical, legal and social aspects resulting from the generation of data from genome sequencing are generic, several nuances are unique. Since the UK government recently announced plans to sequence the genomes of 100,000 Health Service patients, and similar initiatives are being considered elsewhere, a discussion of these nuances is timely and needs to go hand in hand with formulation of guidelines and public engagement activities around implementation of sequencing in clinical practice.
576-585
Lucassen, Anneke
2eb85efc-c6e8-4c3f-b963-0290f6c038a5
Houlston, Richard S.
0292e06f-2fd2-4b71-a629-00b288016474
22 July 2014
Lucassen, Anneke
2eb85efc-c6e8-4c3f-b963-0290f6c038a5
Houlston, Richard S.
0292e06f-2fd2-4b71-a629-00b288016474
Abstract
Genome sequencing is now a sufficiently mature and affordable technology for clinical use. Its application promises not only to transform clinicians' diagnostic and predictive ability, but also to improve preventative therapies, surveillance regimes, and tailor patient treatment to an individual's genetic make-up. However, as with any technological advance, there are associated fresh challenges. While some of the ethical, legal and social aspects resulting from the generation of data from genome sequencing are generic, several nuances are unique. Since the UK government recently announced plans to sequence the genomes of 100,000 Health Service patients, and similar initiatives are being considered elsewhere, a discussion of these nuances is timely and needs to go hand in hand with formulation of guidelines and public engagement activities around implementation of sequencing in clinical practice.
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genes-05-00576.pdf
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Published date: 22 July 2014
Organisations:
Faculty of Medicine
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Local EPrints ID: 367341
URI: http://eprints.soton.ac.uk/id/eprint/367341
ISSN: 2073-4425
PURE UUID: 9cfa47fd-be73-48ee-9f32-cba01f556e09
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Date deposited: 26 Aug 2014 11:59
Last modified: 15 Mar 2024 03:11
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Author:
Richard S. Houlston
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