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The costs associated with the public health management of a cluster of meningococcal infection in England

The costs associated with the public health management of a cluster of meningococcal infection in England
The costs associated with the public health management of a cluster of meningococcal infection in England
The human and public health costs of meningococcal disease are substantial, with 201 cases reported in England between April and June 2013. It is estimated that serogroup B accounts for 85–90% of all cases of meningococcal disease. A vaccine against serogroup B meningococcal disease was approved by the European Medicines Agency in November 2012. In March 2014 the UK Joint Committee on Vaccination and Immunisation recommended that the vaccine be offered to babies at 2, 4 and 12 months of age, provided it can be procured at a cost effective price.

Using a real cluster of two cases of meningococcal infection in the UK, we estimate that the cost of managing two cases was 17 times more than the cost of managing a single case (£5584.39 versus £317.72, respectively). We recommend that vaccine cost effectiveness models should take a full account of the costs involved in managing cases and clusters of meningococcal disease.
meningococcal infection, meningococcal vaccine, outbreak, public health management costs
1-3
Letouze, Dominique
73b4d182-d694-4e87-a741-3335f9593d3c
Yao, Guiqing
d777f84c-cf3d-4fad-bbc1-ea01dec01695
Clarke, Stuart C.
f7d7f7a2-4b1f-4b36-883a-0f967e73fb17
Letouze, Dominique
73b4d182-d694-4e87-a741-3335f9593d3c
Yao, Guiqing
d777f84c-cf3d-4fad-bbc1-ea01dec01695
Clarke, Stuart C.
f7d7f7a2-4b1f-4b36-883a-0f967e73fb17

Letouze, Dominique, Yao, Guiqing and Clarke, Stuart C. (2014) The costs associated with the public health management of a cluster of meningococcal infection in England. Vaccine, 1-3. (doi:10.1016/j.vaccine.2014.08.044). (PMID:25173479)

Record type: Article

Abstract

The human and public health costs of meningococcal disease are substantial, with 201 cases reported in England between April and June 2013. It is estimated that serogroup B accounts for 85–90% of all cases of meningococcal disease. A vaccine against serogroup B meningococcal disease was approved by the European Medicines Agency in November 2012. In March 2014 the UK Joint Committee on Vaccination and Immunisation recommended that the vaccine be offered to babies at 2, 4 and 12 months of age, provided it can be procured at a cost effective price.

Using a real cluster of two cases of meningococcal infection in the UK, we estimate that the cost of managing two cases was 17 times more than the cost of managing a single case (£5584.39 versus £317.72, respectively). We recommend that vaccine cost effectiveness models should take a full account of the costs involved in managing cases and clusters of meningococcal disease.

Full text not available from this repository.

More information

e-pub ahead of print date: 27 August 2014
Keywords: meningococcal infection, meningococcal vaccine, outbreak, public health management costs
Organisations: Primary Care & Population Sciences

Identifiers

Local EPrints ID: 368955
URI: https://eprints.soton.ac.uk/id/eprint/368955
PURE UUID: 10d01abb-e2f1-4653-81c9-fb28b90c53c2
ORCID for Stuart C. Clarke: ORCID iD orcid.org/0000-0002-7009-1548

Catalogue record

Date deposited: 15 Sep 2014 13:10
Last modified: 17 Sep 2019 00:49

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