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European project on osteoarthritis: design of a six-cohort study on the personal and societal burden of osteoarthritis in an older European population

European project on osteoarthritis: design of a six-cohort study on the personal and societal burden of osteoarthritis in an older European population
European project on osteoarthritis: design of a six-cohort study on the personal and societal burden of osteoarthritis in an older European population
Background: Osteoarthritis (OA), the most common form of arthritis, is a major contributor to functional impairment and loss of independence in older persons. The European Project on OSteoArthritis (EPOSA) is a collaborative study involving six European cohort studies on ageing. This project focuses on the personal and societal burden and its determinants of osteoarthritis. This paper describes the design of the project, and presents some descriptive analyses on selected variables across countries.

Methods/Design: EPOSA is an observational study including pre-harmonized data from European cohort studies (Germany, Italy, the Netherlands, Spain, Sweden and the United Kingdom) on older community-dwelling persons aged 65 to 85 years. In total, 2942 persons were included in the baseline study with a mean age of 74.2 years (SD 5.1), just over half were women (51,9%). The baseline assessment was conducted by a face-to-face interview followed by a clinical examination. Measures included physical, cognitive, psychological and social functioning, lifestyle behaviour, physical environment, wellbeing and care utilisation. The clinical examination included anthropometry, muscle strength, physical performance and OA exam. A follow-up assessment was performed 12-18 months after baseline.

Discussion: The EPOSA study is the first population-based study including a clinical examination of OA, using pre-harmonized data across European countries. The EPOSA study provides a unique opportunity to study the determinants and consequences of OA in general populations of older persons, including both care-seeking and non care-seeking persons.
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van der Pas, Suzan
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Castell, Maria Victoria
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Cooper, Cyrus
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Denkinger, Michael
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Dennison, Elaine M.
ee647287-edb4-4392-8361-e59fd505b1d1
Edwards, Mark H
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Herbolsheimer, Florian
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Limongi, Federica
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Lips, Paul
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Maggi, Stefania
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Nasell, Hans
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Nikolaus, Thorsten
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Otero, Angel
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Pedersen, Nancy L
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Peter, Richard
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Sanchez-Martinez, Mercedes
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Schaap, Laura A
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Zambon, Sabina
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van Schoor, Natasja M
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Deeg, Dorly JH
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van der Pas, Suzan
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Castell, Maria Victoria
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Cooper, Cyrus
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Denkinger, Michael
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Dennison, Elaine M.
ee647287-edb4-4392-8361-e59fd505b1d1
Edwards, Mark H
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Herbolsheimer, Florian
effe311b-46fc-45de-9bb6-81ce209e59fc
Limongi, Federica
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Lips, Paul
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Maggi, Stefania
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Nasell, Hans
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Nikolaus, Thorsten
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Otero, Angel
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Pedersen, Nancy L
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Peter, Richard
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Sanchez-Martinez, Mercedes
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Schaap, Laura A
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Zambon, Sabina
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van Schoor, Natasja M
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Deeg, Dorly JH
c6171d2b-7809-4bc9-9908-c10939a08958

van der Pas, Suzan, Castell, Maria Victoria, Cooper, Cyrus, Denkinger, Michael, Dennison, Elaine M., Edwards, Mark H, Herbolsheimer, Florian, Limongi, Federica, Lips, Paul, Maggi, Stefania, Nasell, Hans, Nikolaus, Thorsten, Otero, Angel, Pedersen, Nancy L, Peter, Richard, Sanchez-Martinez, Mercedes, Schaap, Laura A, Zambon, Sabina, van Schoor, Natasja M and Deeg, Dorly JH (2013) European project on osteoarthritis: design of a six-cohort study on the personal and societal burden of osteoarthritis in an older European population. BMC Musculoskeletal Disorders, 14 (1), 138. (doi:10.1186/1471-2474-14-138). (PMID:23597054)

Record type: Article

Abstract

Background: Osteoarthritis (OA), the most common form of arthritis, is a major contributor to functional impairment and loss of independence in older persons. The European Project on OSteoArthritis (EPOSA) is a collaborative study involving six European cohort studies on ageing. This project focuses on the personal and societal burden and its determinants of osteoarthritis. This paper describes the design of the project, and presents some descriptive analyses on selected variables across countries.

Methods/Design: EPOSA is an observational study including pre-harmonized data from European cohort studies (Germany, Italy, the Netherlands, Spain, Sweden and the United Kingdom) on older community-dwelling persons aged 65 to 85 years. In total, 2942 persons were included in the baseline study with a mean age of 74.2 years (SD 5.1), just over half were women (51,9%). The baseline assessment was conducted by a face-to-face interview followed by a clinical examination. Measures included physical, cognitive, psychological and social functioning, lifestyle behaviour, physical environment, wellbeing and care utilisation. The clinical examination included anthropometry, muscle strength, physical performance and OA exam. A follow-up assessment was performed 12-18 months after baseline.

Discussion: The EPOSA study is the first population-based study including a clinical examination of OA, using pre-harmonized data across European countries. The EPOSA study provides a unique opportunity to study the determinants and consequences of OA in general populations of older persons, including both care-seeking and non care-seeking persons.

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More information

Published date: 18 April 2013
Additional Information: © 2013 van der Pas et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Organisations: Faculty of Medicine

Identifiers

Local EPrints ID: 369270
URI: http://eprints.soton.ac.uk/id/eprint/369270
PURE UUID: b8d7b9ad-897a-4b42-a857-7f3d2c703097
ORCID for Cyrus Cooper: ORCID iD orcid.org/0000-0003-3510-0709
ORCID for Elaine M. Dennison: ORCID iD orcid.org/0000-0002-3048-4961

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Date deposited: 23 Sep 2014 10:20
Last modified: 18 Feb 2021 16:48

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Contributors

Author: Suzan van der Pas
Author: Maria Victoria Castell
Author: Cyrus Cooper ORCID iD
Author: Michael Denkinger
Author: Mark H Edwards
Author: Florian Herbolsheimer
Author: Federica Limongi
Author: Paul Lips
Author: Stefania Maggi
Author: Hans Nasell
Author: Thorsten Nikolaus
Author: Angel Otero
Author: Nancy L Pedersen
Author: Richard Peter
Author: Mercedes Sanchez-Martinez
Author: Laura A Schaap
Author: Sabina Zambon
Author: Natasja M van Schoor
Author: Dorly JH Deeg

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