Epilepsy, diabetes mellitus and accidental injury at work
Epilepsy, diabetes mellitus and accidental injury at work
Aims: to assess the contribution of epilepsy and diabetes to occupational injury.
Methods: the Clinical Practice Research Datalink logs primary care data for 6% of the British population, coding all consultations and treatments. Using this, we conducted a population-based case–control study, identifying patients aged 16–64 years, who had consulted over two decades for workplace injury, plus matched controls. By conditional logistic regression, we assessed risks for diabetes and epilepsy overall, several diabetic complications and indices of poor control, occurrence of status epilepticus and treatment with hypoglycaemic and anti-epileptic agents.
Results: we identified 1348 injury cases and 6652 matched controls. A total of 160 subjects (2%) had previous epilepsy, including 29 injury cases, whereas 199 (2.5%) had diabetes, including 77 with eye involvement and 52 with a record of poor control. Odds ratios (ORs) for occupational injury were close to unity, both in those with epilepsy (1.07) and diabetes (0.98) and in those prescribed anti-epileptic or hypoglycaemic treatments in the previous year (0.87–1.16). We found no evidence of any injury arising directly from a seizure and no one had consulted about their epilepsy within 100 days before their injury consultation. Two cases and six controls had suffered status epilepticus (OR versus never had epilepsy 1.61). Risks were somewhat higher for certain diabetic complications (OR 1.44), although lower among those with eye involvement (OR 0.70) or poor diabetic control (OR 0.50). No associations were statistically significant.
Conclusions: no evidence was found that diabetes or epilepsy are important contributors to workplace injury in Britain
448-453
Palmer, K.T.
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D'Angelo, S.
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Harris, E.C.
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Linaker, C.
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Coggon, D.
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September 2014
Palmer, K.T.
0cfe63f0-1d33-40ff-ae8c-6c33601df850
D'Angelo, S.
13375ecd-1117-4b6e-99c0-32239f52eed6
Harris, E.C.
3e4bd946-3f09-45a1-8725-d35e80dd7971
Linaker, C.
6c6d1b90-ee40-4c96-8b2e-b06efbe030ae
Coggon, D.
2b43ce0a-cc61-4d86-b15d-794208ffa5d3
Palmer, K.T., D'Angelo, S., Harris, E.C., Linaker, C. and Coggon, D.
(2014)
Epilepsy, diabetes mellitus and accidental injury at work.
Occupational Medicine, 64 (6), .
(doi:10.1093/occmed/kqu079).
(PMID:24964785)
Abstract
Aims: to assess the contribution of epilepsy and diabetes to occupational injury.
Methods: the Clinical Practice Research Datalink logs primary care data for 6% of the British population, coding all consultations and treatments. Using this, we conducted a population-based case–control study, identifying patients aged 16–64 years, who had consulted over two decades for workplace injury, plus matched controls. By conditional logistic regression, we assessed risks for diabetes and epilepsy overall, several diabetic complications and indices of poor control, occurrence of status epilepticus and treatment with hypoglycaemic and anti-epileptic agents.
Results: we identified 1348 injury cases and 6652 matched controls. A total of 160 subjects (2%) had previous epilepsy, including 29 injury cases, whereas 199 (2.5%) had diabetes, including 77 with eye involvement and 52 with a record of poor control. Odds ratios (ORs) for occupational injury were close to unity, both in those with epilepsy (1.07) and diabetes (0.98) and in those prescribed anti-epileptic or hypoglycaemic treatments in the previous year (0.87–1.16). We found no evidence of any injury arising directly from a seizure and no one had consulted about their epilepsy within 100 days before their injury consultation. Two cases and six controls had suffered status epilepticus (OR versus never had epilepsy 1.61). Risks were somewhat higher for certain diabetic complications (OR 1.44), although lower among those with eye involvement (OR 0.70) or poor diabetic control (OR 0.50). No associations were statistically significant.
Conclusions: no evidence was found that diabetes or epilepsy are important contributors to workplace injury in Britain
Text
Epilepsy paper with journal changes 14-OP-005.R3 (not tracked).doc
- Author's Original
More information
e-pub ahead of print date: June 2014
Published date: September 2014
Organisations:
Human Development & Health
Identifiers
Local EPrints ID: 370121
URI: http://eprints.soton.ac.uk/id/eprint/370121
ISSN: 0962-7480
PURE UUID: 210a40ac-de13-46e2-ae0e-ecb36fadc08d
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Date deposited: 23 Oct 2014 11:18
Last modified: 09 Nov 2024 02:34
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