Locked nucleic acid: tighter is different
Locked nucleic acid: tighter is different
This viewpoint briefly reviews the impact of Locked Nucleic Acid (LNA) oligonucleotides, first described in a ChemComm paper in 1998. A number of unique applications in oligonucleotide biotechnology have been made possible by the high binding affinity and specificity of LNA, and these provide the main focus of the viewpoint.
5618-5620
Watts, Jonathan
c4de85ee-aaa3-4e7d-99b3-147a4de4f01c
16 May 2013
Watts, Jonathan
c4de85ee-aaa3-4e7d-99b3-147a4de4f01c
Watts, Jonathan
(2013)
Locked nucleic acid: tighter is different.
Chemical Communications, 49, .
(doi:10.1039/c3cc40340h).
Abstract
This viewpoint briefly reviews the impact of Locked Nucleic Acid (LNA) oligonucleotides, first described in a ChemComm paper in 1998. A number of unique applications in oligonucleotide biotechnology have been made possible by the high binding affinity and specificity of LNA, and these provide the main focus of the viewpoint.
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LNA viewpoint MS for eprints.pdf
- Accepted Manuscript
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Published date: 16 May 2013
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Local EPrints ID: 371631
URI: http://eprints.soton.ac.uk/id/eprint/371631
ISSN: 1359-7345
PURE UUID: 1f2913af-ae01-4cf4-9595-fad7bbff3aba
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Date deposited: 10 Nov 2014 16:41
Last modified: 14 Mar 2024 18:23
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Jonathan Watts
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