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Biomarkers of immunity and inflammation for use in nutrition interventions: International Life Sciences Institute European Branch work on selection criteria and interpretation

Biomarkers of immunity and inflammation for use in nutrition interventions: International Life Sciences Institute European Branch work on selection criteria and interpretation
Biomarkers of immunity and inflammation for use in nutrition interventions: International Life Sciences Institute European Branch work on selection criteria and interpretation
In order to gain better insight into meaningful effects of nutrition on immune function, there is a need for guidance on the assessment and interpretation of immune markers. However, there is no consensus as to which markers best represent the various aspects of immunity, including acute, chronic or low-grade inflammation. International Life Sciences Institute European Branch has commissioned several expert groups comprising individuals from different backgrounds including academia, government and the food industry to prepare descriptive and guidance documents on this topic. Two of these considered the markers of the immune response mainly in the context of host defence against pathogens, two considered general markers of inflammation, and one focussed on chronic low-grade inflammation in relation to overweight and obesity. This article describes the background to these documents and will summarise the work, findings and recommendations of the expert groups.
biomarker, claim, diet, functional food, immune function, infection, inflammation, nutrition
2212-3873
236-244
Calder, Philip C.
1797e54f-378e-4dcb-80a4-3e30018f07a6
Calder, Philip C.
1797e54f-378e-4dcb-80a4-3e30018f07a6

Calder, Philip C. (2014) Biomarkers of immunity and inflammation for use in nutrition interventions: International Life Sciences Institute European Branch work on selection criteria and interpretation. Endocrine, Metabolic & Immune Disorders Drug Targets, 14 (4), 236-244. (doi:10.2174/1871530314666140714120744). (PMID:25008763)

Record type: Article

Abstract

In order to gain better insight into meaningful effects of nutrition on immune function, there is a need for guidance on the assessment and interpretation of immune markers. However, there is no consensus as to which markers best represent the various aspects of immunity, including acute, chronic or low-grade inflammation. International Life Sciences Institute European Branch has commissioned several expert groups comprising individuals from different backgrounds including academia, government and the food industry to prepare descriptive and guidance documents on this topic. Two of these considered the markers of the immune response mainly in the context of host defence against pathogens, two considered general markers of inflammation, and one focussed on chronic low-grade inflammation in relation to overweight and obesity. This article describes the background to these documents and will summarise the work, findings and recommendations of the expert groups.

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More information

Published date: November 2014
Keywords: biomarker, claim, diet, functional food, immune function, infection, inflammation, nutrition
Organisations: Human Development & Health

Identifiers

Local EPrints ID: 372231
URI: http://eprints.soton.ac.uk/id/eprint/372231
ISSN: 2212-3873
PURE UUID: a967a759-e5cb-46a3-8def-0b667dfd4547
ORCID for Philip C. Calder: ORCID iD orcid.org/0000-0002-6038-710X

Catalogue record

Date deposited: 04 Dec 2014 15:56
Last modified: 15 Mar 2024 02:50

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