Dielectrophoretic manipulation of rod-shaped viral particles
Dielectrophoretic manipulation of rod-shaped viral particles
The dielectrophoretic manipulation of a rod-shaped virus, tobacco mosaic virus (TMV) by means of non-uniform AC electric fields is described. An expression is derived for the dielectrophoretic force on a homogeneous dielectric cylinder suspended in a liquid medium which shows that the dielectrophoretic force varies over a wide range of frequencies and medium conductivities. Measurements of the dielectrophoretic behaviour of TMV particles in microelectrode arrays have been made as a function of frequency and applied field strength. The results are shown to be in quantitative agreement with the derived expression for the dielectrophoretic force. By measuring the threshold field strength for the onset of dielectrophoresis, the force on a single TMV particle has been estimated. The results point to the potential use of dielectrophoresis for the collection and manipulation of sub-micron particles using microelectrode arrays.
Morgan, Hywel
de00d59f-a5a2-48c4-a99a-1d5dd7854174
Green, Nicolas G
d9b47269-c426-41fd-a41d-5f4579faa581
December 1997
Morgan, Hywel
de00d59f-a5a2-48c4-a99a-1d5dd7854174
Green, Nicolas G
d9b47269-c426-41fd-a41d-5f4579faa581
Morgan, Hywel and Green, Nicolas G
(1997)
Dielectrophoretic manipulation of rod-shaped viral particles.
Journal of Electrostatics, 42 (3).
(doi:10.1016/S0304-3886(97)00159-9).
Abstract
The dielectrophoretic manipulation of a rod-shaped virus, tobacco mosaic virus (TMV) by means of non-uniform AC electric fields is described. An expression is derived for the dielectrophoretic force on a homogeneous dielectric cylinder suspended in a liquid medium which shows that the dielectrophoretic force varies over a wide range of frequencies and medium conductivities. Measurements of the dielectrophoretic behaviour of TMV particles in microelectrode arrays have been made as a function of frequency and applied field strength. The results are shown to be in quantitative agreement with the derived expression for the dielectrophoretic force. By measuring the threshold field strength for the onset of dielectrophoresis, the force on a single TMV particle has been estimated. The results point to the potential use of dielectrophoresis for the collection and manipulation of sub-micron particles using microelectrode arrays.
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J5_Morgan_Green_J_Electrostatics_1997.pdf
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Published date: December 1997
Organisations:
Electronics & Computer Science
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Local EPrints ID: 372366
URI: http://eprints.soton.ac.uk/id/eprint/372366
ISSN: 0304-3886
PURE UUID: 10a1f210-ccf8-42a8-979a-ddf7a6f2bc67
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Date deposited: 01 Dec 2014 16:40
Last modified: 15 Mar 2024 03:20
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Author:
Hywel Morgan
Author:
Nicolas G Green
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