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Neuronal NOS localises to human airway cilia

Neuronal NOS localises to human airway cilia
Neuronal NOS localises to human airway cilia
We report a novel localisation of nNOS at the proximal portion of cilia in airway epithelium and conclude that its independent and local regulation of NO levels is crucial for normal cilia function.
airway, cilia, EC 1.14.13.39, epithelium, NOS, nNOS
1089-8603
3-7
Jackson, Claire L.
ca0c242e-3638-4949-a0cb-f41e36067b8f
Lucas, Jane S.
5cb3546c-87b2-4e59-af48-402076e25313
Walker, Woolf T.
58aae223-5b0e-4f34-9ee7-58bb68278c3a
Owen, Holly
97702acf-7554-4f82-9f68-4836430c59ec
Premadeva, Irnthu
1fc18967-7bf1-4511-8411-fdf19c8d5b03
Lackie, Peter M.
4afbbe1a-22a6-4ceb-8cad-f3696dc43a7a
Jackson, Claire L.
ca0c242e-3638-4949-a0cb-f41e36067b8f
Lucas, Jane S.
5cb3546c-87b2-4e59-af48-402076e25313
Walker, Woolf T.
58aae223-5b0e-4f34-9ee7-58bb68278c3a
Owen, Holly
97702acf-7554-4f82-9f68-4836430c59ec
Premadeva, Irnthu
1fc18967-7bf1-4511-8411-fdf19c8d5b03
Lackie, Peter M.
4afbbe1a-22a6-4ceb-8cad-f3696dc43a7a

Jackson, Claire L., Lucas, Jane S., Walker, Woolf T., Owen, Holly, Premadeva, Irnthu and Lackie, Peter M. (2014) Neuronal NOS localises to human airway cilia. Nitric Oxide, 44C, 3-7. (doi:10.1016/j.niox.2014.11.003). (PMID:25460324)

Record type: Article

Abstract

We report a novel localisation of nNOS at the proximal portion of cilia in airway epithelium and conclude that its independent and local regulation of NO levels is crucial for normal cilia function.

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More information

Published date: 6 November 2014
Keywords: airway, cilia, EC 1.14.13.39, epithelium, NOS, nNOS
Organisations: Clinical & Experimental Sciences

Identifiers

Local EPrints ID: 372448
URI: http://eprints.soton.ac.uk/id/eprint/372448
ISSN: 1089-8603
PURE UUID: e1d631ba-7d4c-40a0-a1e2-2b47bc455bd3
ORCID for Jane S. Lucas: ORCID iD orcid.org/0000-0001-8701-9975
ORCID for Peter M. Lackie: ORCID iD orcid.org/0000-0001-7138-3764

Catalogue record

Date deposited: 10 Dec 2014 15:39
Last modified: 15 Mar 2024 03:12

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Contributors

Author: Claire L. Jackson
Author: Jane S. Lucas ORCID iD
Author: Woolf T. Walker
Author: Holly Owen
Author: Irnthu Premadeva
Author: Peter M. Lackie ORCID iD

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