Methods and compositions for regulating biofilm development using Nitric Oxide
Methods and compositions for regulating biofilm development using Nitric Oxide
The present invention relates to methods for promoting dispersal of, or preventing formation of microbial biofilms, comprising: exposing a biofilm to an effective amount of nitric oxide or at least one nitric oxide generating or releasing agent; treating a surface or medium susceptible to biofilm formation with an effective amount of nitric oxide or at least one nitric oxide generating or releasing agent; incorporating an effective amount of nitric oxide or at least one nitric oxide generating or releasing agent in a surface or medium susceptible to biofilm formation; or inducing the accumulation of one or more reactive oxygen or nitrogen species within microorganisms within said biofilm or capable of forming a biofilm. The invention also relates to methods for maintaining or enhancing or maintaining and enhancing the functioning of a biofilm, comprising exposing a biofilm to at least one nitric oxide scavenger, at least one antioxidant or at least one nitric oxide scavenger and at least one antioxidant. The invention also relates to compositions for promoting dispersal of, or preventing formation of microbial biofilms, or for maintaining or enhancing or maintaining and enhancing the functioning of microbial biofilms.
US Patent 8,425,945
23 April 2013
Barraud, N.
04b83401-f5b4-4e8b-8f7d-03f7b3a693f5
Webb, Jeremy S.
ec0a5c4e-86cc-4ae9-b390-7298f5d65f8d
Rice, S.
df8be5fd-d343-4379-9487-318581b6630b
Barraud, N., Webb, Jeremy S. and Rice, S.
(Inventors)
(2013)
Methods and compositions for regulating biofilm development using Nitric Oxide.
US Patent 8,425,945.
Abstract
The present invention relates to methods for promoting dispersal of, or preventing formation of microbial biofilms, comprising: exposing a biofilm to an effective amount of nitric oxide or at least one nitric oxide generating or releasing agent; treating a surface or medium susceptible to biofilm formation with an effective amount of nitric oxide or at least one nitric oxide generating or releasing agent; incorporating an effective amount of nitric oxide or at least one nitric oxide generating or releasing agent in a surface or medium susceptible to biofilm formation; or inducing the accumulation of one or more reactive oxygen or nitrogen species within microorganisms within said biofilm or capable of forming a biofilm. The invention also relates to methods for maintaining or enhancing or maintaining and enhancing the functioning of a biofilm, comprising exposing a biofilm to at least one nitric oxide scavenger, at least one antioxidant or at least one nitric oxide scavenger and at least one antioxidant. The invention also relates to compositions for promoting dispersal of, or preventing formation of microbial biofilms, or for maintaining or enhancing or maintaining and enhancing the functioning of microbial biofilms.
This record has no associated files available for download.
More information
Published date: 23 April 2013
Additional Information:
US8425945 (B2)
Organisations:
Centre for Biological Sciences
Identifiers
Local EPrints ID: 372538
URI: http://eprints.soton.ac.uk/id/eprint/372538
PURE UUID: 18ee0ccf-3b70-4255-b8da-654850ac07b3
Catalogue record
Date deposited: 08 Dec 2014 14:05
Last modified: 12 Dec 2021 03:35
Export record
Contributors
Inventor:
N. Barraud
Inventor:
S. Rice
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics
