Perceptions of weight, diabetes and willingness to participate in randomised controlled trials of bariatric surgery for patients with type 2 diabetes mellitus and body mass index 30-39.9 kg/m2
Perceptions of weight, diabetes and willingness to participate in randomised controlled trials of bariatric surgery for patients with type 2 diabetes mellitus and body mass index 30-39.9 kg/m2
Purpose
Evidence from high-quality randomised controlled trials (RCTs) is needed to establish the long-term benefit of bariatric surgery in people with type 2 diabetes mellitus (T2DM) and body mass index (BMI) 30–39.9 kg/m2. However, willingness amongst this group to be randomised and undergo surgery is uncertain. This study assessed UK patients’ perceptions of their weight and diabetes, and associations with willingness to participate in RCTs involving bariatric surgery, amongst this population.
Materials and Methods
Postal survey of 1820 patients from four regions in England. Eligible patients were as follows: BMI 30–39.9 kg/m2, 18–74 years, diagnosis of T2DM ?2 years. A reminder survey was sent after 4 weeks. Independent predictors influencing patients’ willingness to consider RCT participation were identified using multiple logistic regression analysis.
Results
Thirty-four per cent (614/1820) of patients responded. Weight was considered to be harder to control than diabetes [468/584 (80 %) vs. 107/600 (17 %)]. More people reported a negative impact on life for weight rather than diabetes [379/579 (63 %) vs. 180/574 (31 %)]. Feeling unsatisfied/very unsatisfied with weight loss ability was common 261/578 (45 %). Sixty-four per cent (379/594, CI?=?60–68) were willing to consider participating in an RCT. In multivariate analysis, negative impact of weight on life (OR?=?2.55, 95 % CI?=?1.68–3.89, P?<?0.001) and feeling unsatisfied with weight loss ability (OR?=?2.47, 95 % CI?=?1.55–3.95, P?<?0.001) positively influenced patients’ willingness to participate in an RCT.
Conclusion
Strong patient interest supports the feasibility of such trials for this group. Perceptions of obesity negatively impacting on life and difficulties in achieving weight loss were common and influenced attitudes to potential participation in bariatric surgery RCTs.
type 2 diabetes, obesity treatment, patient preferences, bariatric surgery, survey research
1039-1046
Summers, Rachael H.
811d6b74-d5f4-4e92-a507-9bdca978fda5
Moore, M.
1be81dad-7120-45f0-bbed-f3b0cc0cfe99
Byrne, J.
d31b7acf-d522-476d-8837-06bfa5c95cd3
Byrne, C.
f22ab35b-8d98-41be-a89c-df9b1677dace
Mullee, M.
fd3f91c3-5e95-4f56-8d73-260824eeb362
Welbourn, R.
b9239e65-e325-41f9-9485-177ee23c5ec6
Elsey, H.
51776d3c-3a5e-4c34-8d71-73b678c0f22e
Roderick, P.
dbb3cd11-4c51-4844-982b-0eb30ad5085a
June 2015
Summers, Rachael H.
811d6b74-d5f4-4e92-a507-9bdca978fda5
Moore, M.
1be81dad-7120-45f0-bbed-f3b0cc0cfe99
Byrne, J.
d31b7acf-d522-476d-8837-06bfa5c95cd3
Byrne, C.
f22ab35b-8d98-41be-a89c-df9b1677dace
Mullee, M.
fd3f91c3-5e95-4f56-8d73-260824eeb362
Welbourn, R.
b9239e65-e325-41f9-9485-177ee23c5ec6
Elsey, H.
51776d3c-3a5e-4c34-8d71-73b678c0f22e
Roderick, P.
dbb3cd11-4c51-4844-982b-0eb30ad5085a
Summers, Rachael H., Moore, M., Byrne, J., Byrne, C., Mullee, M., Welbourn, R., Elsey, H. and Roderick, P.
(2015)
Perceptions of weight, diabetes and willingness to participate in randomised controlled trials of bariatric surgery for patients with type 2 diabetes mellitus and body mass index 30-39.9 kg/m2.
Obesity Surgery, 25 (6), .
(doi:10.1007/s11695-014-1479-4).
(PMID:25416084)
Abstract
Purpose
Evidence from high-quality randomised controlled trials (RCTs) is needed to establish the long-term benefit of bariatric surgery in people with type 2 diabetes mellitus (T2DM) and body mass index (BMI) 30–39.9 kg/m2. However, willingness amongst this group to be randomised and undergo surgery is uncertain. This study assessed UK patients’ perceptions of their weight and diabetes, and associations with willingness to participate in RCTs involving bariatric surgery, amongst this population.
Materials and Methods
Postal survey of 1820 patients from four regions in England. Eligible patients were as follows: BMI 30–39.9 kg/m2, 18–74 years, diagnosis of T2DM ?2 years. A reminder survey was sent after 4 weeks. Independent predictors influencing patients’ willingness to consider RCT participation were identified using multiple logistic regression analysis.
Results
Thirty-four per cent (614/1820) of patients responded. Weight was considered to be harder to control than diabetes [468/584 (80 %) vs. 107/600 (17 %)]. More people reported a negative impact on life for weight rather than diabetes [379/579 (63 %) vs. 180/574 (31 %)]. Feeling unsatisfied/very unsatisfied with weight loss ability was common 261/578 (45 %). Sixty-four per cent (379/594, CI?=?60–68) were willing to consider participating in an RCT. In multivariate analysis, negative impact of weight on life (OR?=?2.55, 95 % CI?=?1.68–3.89, P?<?0.001) and feeling unsatisfied with weight loss ability (OR?=?2.47, 95 % CI?=?1.55–3.95, P?<?0.001) positively influenced patients’ willingness to participate in an RCT.
Conclusion
Strong patient interest supports the feasibility of such trials for this group. Perceptions of obesity negatively impacting on life and difficulties in achieving weight loss were common and influenced attitudes to potential participation in bariatric surgery RCTs.
Text
__userfiles.soton.ac.uk_Users_nl2_mydesktop_OCOD_Manuscript_ diabetes weight and surgery_CLEAN Revised 21 08 14.docx
- Author's Original
More information
e-pub ahead of print date: 22 November 2014
Published date: June 2015
Keywords:
type 2 diabetes, obesity treatment, patient preferences, bariatric surgery, survey research
Organisations:
Primary Care & Population Sciences
Identifiers
Local EPrints ID: 372643
URI: http://eprints.soton.ac.uk/id/eprint/372643
ISSN: 0960-8923
PURE UUID: e6fc1ab4-43cc-4d96-86b4-98cd47429ca8
Catalogue record
Date deposited: 11 Dec 2014 17:01
Last modified: 15 Mar 2024 03:22
Export record
Altmetrics
Contributors
Author:
Rachael H. Summers
Author:
J. Byrne
Author:
C. Byrne
Author:
R. Welbourn
Author:
H. Elsey
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics