Metabolic monitoring in the intensive care unit: a comparison of the Medgraphics Ultima, Deltatrac II, and Douglas bag collection methods
Metabolic monitoring in the intensive care unit: a comparison of the Medgraphics Ultima, Deltatrac II, and Douglas bag collection methods
Background
The accuracy of oxygen consumption measurement by indirect calorimeters is poorly validated in mechanically ventilated intensive care patients where multiple confounders exist. This study sought to compare the Medgraphics Ultima (MGU) and Deltatrac II (DTII) devices, and the Douglas bag (DB) technique in mechanically ventilated patients at rest.
Methods
Prospective comparison of oxygen consumption measurement using three indirect calorimetry techniques in stable, resting mechanically ventilated patients at rest. Oxygen consumption (VO2), carbon dioxide production (VCO2), resting energy expenditure (REE), and respiratory quotient (RQ) were recorded breath-by-breath by the MGU over a 30–75 min period. During this time, simultaneous measurements were taken using the DTII, the DB, or both.
Results
While there was no systematic error (bias) between measurements made by the three techniques (VO2: MGU vs DTII 3.6%, MGU vs DB 3.3%), the limits of agreement were wide (VO2: MGU vs DTII 33%, MGU vs DB 54%).
Conclusions
Resting oxygen consumption values in stable mechanically ventilated patients measured by the three techniques showed acceptable bias but poor precision. There is an important clinical and research need to develop new indirect calorimeters specifically tailored to measure oxygen consumption during mechanical ventilation.
indirect calorimetry, mechanical, oxygen consumption, validation studies, ventilators
Black, C.
5b701372-b1e8-4dd0-994a-caf711fac9a8
Grocott, M.P.W.
1e87b741-513e-4a22-be13-0f7bb344e8c2
Singer, M.
c73d3e5b-b634-4d6f-98f2-1d230a51797f
29 October 2014
Black, C.
5b701372-b1e8-4dd0-994a-caf711fac9a8
Grocott, M.P.W.
1e87b741-513e-4a22-be13-0f7bb344e8c2
Singer, M.
c73d3e5b-b634-4d6f-98f2-1d230a51797f
Black, C., Grocott, M.P.W. and Singer, M.
(2014)
Metabolic monitoring in the intensive care unit: a comparison of the Medgraphics Ultima, Deltatrac II, and Douglas bag collection methods.
British Journal of Anaesthesia.
(doi:10.1093/bja/aeu365).
(PMID:25354946)
Abstract
Background
The accuracy of oxygen consumption measurement by indirect calorimeters is poorly validated in mechanically ventilated intensive care patients where multiple confounders exist. This study sought to compare the Medgraphics Ultima (MGU) and Deltatrac II (DTII) devices, and the Douglas bag (DB) technique in mechanically ventilated patients at rest.
Methods
Prospective comparison of oxygen consumption measurement using three indirect calorimetry techniques in stable, resting mechanically ventilated patients at rest. Oxygen consumption (VO2), carbon dioxide production (VCO2), resting energy expenditure (REE), and respiratory quotient (RQ) were recorded breath-by-breath by the MGU over a 30–75 min period. During this time, simultaneous measurements were taken using the DTII, the DB, or both.
Results
While there was no systematic error (bias) between measurements made by the three techniques (VO2: MGU vs DTII 3.6%, MGU vs DB 3.3%), the limits of agreement were wide (VO2: MGU vs DTII 33%, MGU vs DB 54%).
Conclusions
Resting oxygen consumption values in stable mechanically ventilated patients measured by the three techniques showed acceptable bias but poor precision. There is an important clinical and research need to develop new indirect calorimeters specifically tailored to measure oxygen consumption during mechanical ventilation.
This record has no associated files available for download.
More information
Published date: 29 October 2014
Keywords:
indirect calorimetry, mechanical, oxygen consumption, validation studies, ventilators
Organisations:
Clinical & Experimental Sciences
Identifiers
Local EPrints ID: 372850
URI: http://eprints.soton.ac.uk/id/eprint/372850
ISSN: 0007-0912
PURE UUID: 498d2d86-027f-4463-9179-5a28febe739c
Catalogue record
Date deposited: 23 Dec 2014 12:34
Last modified: 15 Mar 2024 03:33
Export record
Altmetrics
Contributors
Author:
C. Black
Author:
M. Singer
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics