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Prompt and accurate diagnosis of ventricular arrhythmias with a novel index based on phase space reconstruction of ECG

Prompt and accurate diagnosis of ventricular arrhythmias with a novel index based on phase space reconstruction of ECG
Prompt and accurate diagnosis of ventricular arrhythmias with a novel index based on phase space reconstruction of ECG
Aim: to develop a statistical index based on the phase space reconstruction (PSR) of the electrocardiogram (ECG) for the accurate and timely diagnosis of ventricular tachycardia (VT) and ventricular fibrillation (VF).

Methods: thirty-two ECGs with sinus rhythm (SR) and 32 ECGs with VT/VF were analyzed using the PSR technique. Firstly, the method of time delay embedding were employed with the insertion of delay “?” in the original time-series X(t), which produces the Y(t) = X(t ? ?). Afterwards, a PSR diagram was reconstructed by plotting Y(t) against X(t). The method of box counting was applied to analyze the behavior of the PSR trajectories. Measures as mean (?), standard deviation (?) and coefficient of variation (CV = ?/?), kurtosis (?) for the box counting of PSR diagrams were reported.

Results: during SR, CV was always < 0.05, while with the onset of arrhythmia CV increased > 0.05. A similar pattern was observed with ? , where < 6 was considered as the cut-off point between SR and VT/VF. Therefore, the upper threshold for SR was considered CV th = 0.05 and ?th < 6. For optimisation of the accuracy, a new index (J ) was proposed: View the MathML sourceJ=wCVCVth+1?w??th.

During SR the upper limit of J was the value of 1. Furthermore CV, ? and J crossed the cut-off point timely before the onset of arrhythmia (average time: 4 min 31 s; SD: 2 min 30 s); allowing sufficient time for preventive therapy.

Conclusion: the J index improved ECG utility for arrhythmia monitoring and detection utility, allowing the prompt and accurate diagnosis of ventricular arrhythmias.
0167-5273
38-43
Koulaouzidis, George
3f78927b-a7f3-457f-ab26-da6f256b2804
Das, Saptarshi
e06f2eb0-1e3e-453c-ba78-82eed18ceac9
Cappiello, Grazia
0105af1b-7ef6-4b45-87c0-42b3d3bca789
Mazomenos, Evangelos
23983827-c7e7-4ee1-bfc8-986aa3594279
Maharatna, Koushik
93bef0a2-e011-4622-8c56-5447da4cd5dd
Puddu, Paolo E.
d87b49b8-9063-4881-b559-b389b592eeaa
Morgan, John M.
ac98099e-241d-4551-bc98-709f6dfc8680
Koulaouzidis, George
3f78927b-a7f3-457f-ab26-da6f256b2804
Das, Saptarshi
e06f2eb0-1e3e-453c-ba78-82eed18ceac9
Cappiello, Grazia
0105af1b-7ef6-4b45-87c0-42b3d3bca789
Mazomenos, Evangelos
23983827-c7e7-4ee1-bfc8-986aa3594279
Maharatna, Koushik
93bef0a2-e011-4622-8c56-5447da4cd5dd
Puddu, Paolo E.
d87b49b8-9063-4881-b559-b389b592eeaa
Morgan, John M.
ac98099e-241d-4551-bc98-709f6dfc8680

Koulaouzidis, George, Das, Saptarshi, Cappiello, Grazia, Mazomenos, Evangelos, Maharatna, Koushik, Puddu, Paolo E. and Morgan, John M. (2015) Prompt and accurate diagnosis of ventricular arrhythmias with a novel index based on phase space reconstruction of ECG. International Journal of Cardiology, 182, 38-43. (doi:10.1016/j.ijcard.2014.12.067).

Record type: Article

Abstract

Aim: to develop a statistical index based on the phase space reconstruction (PSR) of the electrocardiogram (ECG) for the accurate and timely diagnosis of ventricular tachycardia (VT) and ventricular fibrillation (VF).

Methods: thirty-two ECGs with sinus rhythm (SR) and 32 ECGs with VT/VF were analyzed using the PSR technique. Firstly, the method of time delay embedding were employed with the insertion of delay “?” in the original time-series X(t), which produces the Y(t) = X(t ? ?). Afterwards, a PSR diagram was reconstructed by plotting Y(t) against X(t). The method of box counting was applied to analyze the behavior of the PSR trajectories. Measures as mean (?), standard deviation (?) and coefficient of variation (CV = ?/?), kurtosis (?) for the box counting of PSR diagrams were reported.

Results: during SR, CV was always < 0.05, while with the onset of arrhythmia CV increased > 0.05. A similar pattern was observed with ? , where < 6 was considered as the cut-off point between SR and VT/VF. Therefore, the upper threshold for SR was considered CV th = 0.05 and ?th < 6. For optimisation of the accuracy, a new index (J ) was proposed: View the MathML sourceJ=wCVCVth+1?w??th.

During SR the upper limit of J was the value of 1. Furthermore CV, ? and J crossed the cut-off point timely before the onset of arrhythmia (average time: 4 min 31 s; SD: 2 min 30 s); allowing sufficient time for preventive therapy.

Conclusion: the J index improved ECG utility for arrhythmia monitoring and detection utility, allowing the prompt and accurate diagnosis of ventricular arrhythmias.

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Published date: 1 March 2015
Organisations: Electronic & Software Systems

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Local EPrints ID: 373147
URI: https://eprints.soton.ac.uk/id/eprint/373147
ISSN: 0167-5273
PURE UUID: 4df0a869-5755-4cef-a014-a45112949481

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Date deposited: 09 Jan 2015 14:44
Last modified: 19 Jul 2019 20:54

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