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The synthesis of mono- and difluorinated 2,3-dideoxy-d-glucopyranoses

The synthesis of mono- and difluorinated 2,3-dideoxy-d-glucopyranoses
The synthesis of mono- and difluorinated 2,3-dideoxy-d-glucopyranoses
The synthesis of 2,3-dideoxy-2,3-difluoro-d-glucose and 2,3-dideoxy-3-fluoro-d-glucose is reported in, respectively, 5 and 6 steps from d-glucal, using a fluorination strategy.
fluorine, carbohydrate, deoxofluorination, 1, 6-Anhydrosugar, carbohydrate mimetic
0022-1139
92-96
Mtashobya, Lewis
7e000614-c31f-43fb-96da-75bf6cf2076d
Quiquempoix, Lucas
29de2855-0a16-43a2-8987-dfc823f61458
Linclau, Bruno
19b9cacd-b8e8-4c65-af36-6352cade84ba
Mtashobya, Lewis
7e000614-c31f-43fb-96da-75bf6cf2076d
Quiquempoix, Lucas
29de2855-0a16-43a2-8987-dfc823f61458
Linclau, Bruno
19b9cacd-b8e8-4c65-af36-6352cade84ba

Mtashobya, Lewis, Quiquempoix, Lucas and Linclau, Bruno (2015) The synthesis of mono- and difluorinated 2,3-dideoxy-d-glucopyranoses. Journal of Fluorine Chemistry, 171, 92-96. (doi:10.1016/j.jfluchem.2014.08.023).

Record type: Article

Abstract

The synthesis of 2,3-dideoxy-2,3-difluoro-d-glucose and 2,3-dideoxy-3-fluoro-d-glucose is reported in, respectively, 5 and 6 steps from d-glucal, using a fluorination strategy.

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e-pub ahead of print date: 16 September 2014
Published date: March 2015
Keywords: fluorine, carbohydrate, deoxofluorination, 1, 6-Anhydrosugar, carbohydrate mimetic

Identifiers

Local EPrints ID: 373305
URI: http://eprints.soton.ac.uk/id/eprint/373305
ISSN: 0022-1139
PURE UUID: eb74e3cb-06a7-4fc3-a2af-91d5ccef9c73
ORCID for Bruno Linclau: ORCID iD orcid.org/0000-0001-8762-0170

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Date deposited: 14 Jan 2015 17:11
Last modified: 18 Feb 2021 16:55

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Contributors

Author: Lewis Mtashobya
Author: Lucas Quiquempoix
Author: Bruno Linclau ORCID iD

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