Respiratory consequences of late preterm birth
Respiratory consequences of late preterm birth
In developed countries most preterm births occur between 34 and 37 weeks' gestation. Deliveries during this 'late preterm' period are increasing and, since even mild prematurity is now recognised to be associated with adverse health outcomes, this presents healthcare challenges. Respiratory problems associated with late preterm birth include neonatal respiratory distress, severe RSV infection and childhood wheezing. Late preterm birth prematurely interrupts in utero lung development and is associated with maternal and early life factors which adversely affect the developing respiratory system. This review considers 1) mechanisms underlying the association between late preterm birth and impaired respiratory development, 2) respiratory morbidity associated with late preterm birth, particularly long-term outcomes, and 3) interventions which might protect respiratory development by addressing risk factors affecting the late preterm population, including maternal smoking, early life growth restriction and vulnerability to viral infection.
infant, premature, respiratory function tests, asthma, outcome, intervention
1-7
Pike, Katharine C.
15d8a826-8acd-4c0a-836e-4b589336f449
Lucas, Jane S.A.
5cb3546c-87b2-4e59-af48-402076e25313
8 December 2014
Pike, Katharine C.
15d8a826-8acd-4c0a-836e-4b589336f449
Lucas, Jane S.A.
5cb3546c-87b2-4e59-af48-402076e25313
Abstract
In developed countries most preterm births occur between 34 and 37 weeks' gestation. Deliveries during this 'late preterm' period are increasing and, since even mild prematurity is now recognised to be associated with adverse health outcomes, this presents healthcare challenges. Respiratory problems associated with late preterm birth include neonatal respiratory distress, severe RSV infection and childhood wheezing. Late preterm birth prematurely interrupts in utero lung development and is associated with maternal and early life factors which adversely affect the developing respiratory system. This review considers 1) mechanisms underlying the association between late preterm birth and impaired respiratory development, 2) respiratory morbidity associated with late preterm birth, particularly long-term outcomes, and 3) interventions which might protect respiratory development by addressing risk factors affecting the late preterm population, including maternal smoking, early life growth restriction and vulnerability to viral infection.
This record has no associated files available for download.
More information
Published date: 8 December 2014
Keywords:
infant, premature, respiratory function tests, asthma, outcome, intervention
Organisations:
Clinical & Experimental Sciences
Identifiers
Local EPrints ID: 373446
URI: http://eprints.soton.ac.uk/id/eprint/373446
ISSN: 1526-0550
PURE UUID: c0da5611-b57b-4060-8de8-3804a6b921f9
Catalogue record
Date deposited: 19 Jan 2015 11:37
Last modified: 15 Mar 2024 03:12
Export record
Altmetrics
Contributors
Author:
Katharine C. Pike
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics
