Real-space imaging of macroscopic diffusion and slow flow by singlet tagging MRI
Real-space imaging of macroscopic diffusion and slow flow by singlet tagging MRI
Magnetic resonance imaging can be used to study motional processes such as flow and diffusion, but the accessible timescales are limited by longitudinal relaxation. The spatially selective conversion from magnetization to long-lived singlet order in designer molecules makes it possible to tag a region of interest for an extended period of time, of the order of several minutes. Here we exploit this concept of “singlet tagging” to monitor diffusion over a macroscopic scale as well as very slow flow.
long-lived states, flow, diffusion, tagging, magnetic resonance imaging
1-13
Pileio, Giuseppe
13f78e66-0707-4438-b9c9-6dbd3eb7d4e8
Dumez, Jean-Nicolas
10fd319d-e42c-42dc-8b2b-34c10475cc27
pop, ionut-alexandru
fb310398-c5e3-4942-96de-a95354adafc4
Hill-Cousins, Joseph T.
3fd2a389-1612-4d9d-8322-afcc0c401ada
Brown, Richard C.D.
21ce697a-7c3a-480e-919f-429a3d8550f5
Pileio, Giuseppe
13f78e66-0707-4438-b9c9-6dbd3eb7d4e8
Dumez, Jean-Nicolas
10fd319d-e42c-42dc-8b2b-34c10475cc27
pop, ionut-alexandru
fb310398-c5e3-4942-96de-a95354adafc4
Hill-Cousins, Joseph T.
3fd2a389-1612-4d9d-8322-afcc0c401ada
Brown, Richard C.D.
21ce697a-7c3a-480e-919f-429a3d8550f5
Pileio, Giuseppe, Dumez, Jean-Nicolas, pop, ionut-alexandru, Hill-Cousins, Joseph T. and Brown, Richard C.D.
(2015)
Real-space imaging of macroscopic diffusion and slow flow by singlet tagging MRI.
Journal of Magnetic Resonance, .
(doi:10.1016/j.jmr.2015.01.016).
Abstract
Magnetic resonance imaging can be used to study motional processes such as flow and diffusion, but the accessible timescales are limited by longitudinal relaxation. The spatially selective conversion from magnetization to long-lived singlet order in designer molecules makes it possible to tag a region of interest for an extended period of time, of the order of several minutes. Here we exploit this concept of “singlet tagging” to monitor diffusion over a macroscopic scale as well as very slow flow.
Text
JMR-14-327Rev.pdf
- Accepted Manuscript
More information
e-pub ahead of print date: 31 January 2015
Keywords:
long-lived states, flow, diffusion, tagging, magnetic resonance imaging
Organisations:
Chemistry
Identifiers
Local EPrints ID: 373986
URI: http://eprints.soton.ac.uk/id/eprint/373986
PURE UUID: 52dfcb48-3994-49d8-b3e7-ac57f6fbfe7f
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Date deposited: 04 Feb 2015 15:16
Last modified: 15 Mar 2024 03:24
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Contributors
Author:
Jean-Nicolas Dumez
Author:
ionut-alexandru pop
Author:
Joseph T. Hill-Cousins
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