The University of Southampton
University of Southampton Institutional Repository

Achilles tendinopathy following Kaletra(lopinavir/ritonavir) use

Achilles tendinopathy following Kaletra(lopinavir/ritonavir) use
Achilles tendinopathy following Kaletra(lopinavir/ritonavir) use
A multitude of rheumatologic manifestations have been associated with HIV infection and protease inhibitors use. We describe two cases that display a temporal relationship between initiating Kaletra and developing Achilles tendinopathy. Immediate and dramatic resolution of symptoms occurred on switching from Kaletra to an alternative agent. Clinicians may want to consider a trial of an alternative agent in individuals on Kaletra who experience Achilles tendinopathy. Adverse events must be formally reported so that our understanding of antiretrovirals may continually evolve and aid decisions about antiretroviral prescribing.
hiv, aids, antiretroviral therapy, treatment, toxicity, Achilles tendinopathy, tendinitis, kaletra, loppinavir, protease inhibitors
833-835
Cresswell, F.V.
9e198b5d-59d3-4653-a3b5-fbd490ec92dc
Tomlins, J.
a99e0e8e-4ba2-4557-a2ef-e8d9fa60717f
Churchill, D.R.
4e1ffac3-8a80-47de-831f-ba98dbe04b7e
Walker-Bone, K.
ad7d1336-ed2c-4f39-ade5-da84eb412109
Richardson, D.
9dedf3b7-54a6-4068-b9ba-f71b70b1d813
Cresswell, F.V.
9e198b5d-59d3-4653-a3b5-fbd490ec92dc
Tomlins, J.
a99e0e8e-4ba2-4557-a2ef-e8d9fa60717f
Churchill, D.R.
4e1ffac3-8a80-47de-831f-ba98dbe04b7e
Walker-Bone, K.
ad7d1336-ed2c-4f39-ade5-da84eb412109
Richardson, D.
9dedf3b7-54a6-4068-b9ba-f71b70b1d813

Cresswell, F.V., Tomlins, J., Churchill, D.R., Walker-Bone, K. and Richardson, D. (2014) Achilles tendinopathy following Kaletra(lopinavir/ritonavir) use. International Journal of STD & AIDS, 25 (11), 833-835. (doi:10.1177/0956462414523403). (PMID:24516081)

Record type: Article

Abstract

A multitude of rheumatologic manifestations have been associated with HIV infection and protease inhibitors use. We describe two cases that display a temporal relationship between initiating Kaletra and developing Achilles tendinopathy. Immediate and dramatic resolution of symptoms occurred on switching from Kaletra to an alternative agent. Clinicians may want to consider a trial of an alternative agent in individuals on Kaletra who experience Achilles tendinopathy. Adverse events must be formally reported so that our understanding of antiretrovirals may continually evolve and aid decisions about antiretroviral prescribing.

This record has no associated files available for download.

More information

Accepted/In Press date: 14 January 2014
Published date: October 2014
Keywords: hiv, aids, antiretroviral therapy, treatment, toxicity, Achilles tendinopathy, tendinitis, kaletra, loppinavir, protease inhibitors
Organisations: Human Development & Health

Identifiers

Local EPrints ID: 375429
URI: http://eprints.soton.ac.uk/id/eprint/375429
PURE UUID: ff777457-fece-497f-ac34-66bb32312458
ORCID for K. Walker-Bone: ORCID iD orcid.org/0000-0002-5992-1459

Catalogue record

Date deposited: 24 Mar 2015 14:03
Last modified: 15 Mar 2024 03:04

Export record

Altmetrics

Contributors

Author: F.V. Cresswell
Author: J. Tomlins
Author: D.R. Churchill
Author: K. Walker-Bone ORCID iD
Author: D. Richardson

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×