Primary prevention of congenital anomalies: recommendable, feasible and achievable
Primary prevention of congenital anomalies: recommendable, feasible and achievable
Primary prevention of congenital anomalies was identified as an important action in the field of rare diseases by the European Commission in 2008, but it was not included in the Council Recommendation on an action in the field of rare diseases in 2009. However, primary prevention of congenital anomalies is feasible because scientific evidence points to several risk factors (e.g., obesity, infectious and toxic agents) and protective factors (e.g., folic acid supplementation and glycemic control in diabetic women). Evidence-based community actions targeting fertile women can be envisaged, such as risk-benefit evaluation protocols on therapies for chronic diseases, vaccination policies, regulations on workplace and environmental exposures as well as the empowerment of women in their lifestyle choices. A primary prevention plan can identify priority targets, exploit and integrate ongoing actions and optimize the use of resources, thus reducing the health burden for the new generation. The EUROCAT-EUROPLAN recommendations for the primary prevention of congenital anomalies endorsed in 2013 by the European Union Committee of Experts on Rare Diseases present an array of feasible and evidence-based measures from which national plans can adopt and implement actions based on country priorities. Primary prevention of congenital anomalies can be achieved here and now and should be an integral part of national plans on rare diseases.
184-191
Taruscio, Domenica
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Mantovani, Alberto
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Carbone, Pietro
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Barisic, Ingeborg
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Bianchi, Fabrizio
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Garne, Ester
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Nelen, Vera
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Neville, Amanda Julie
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Wellesley, Diana
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Dolk, Helen
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June 2015
Taruscio, Domenica
baa892ba-1053-421f-8533-79e1ce94f0f2
Mantovani, Alberto
7367970b-a740-4353-8084-1af97b0c665d
Carbone, Pietro
a7e7e34d-e5c8-47ef-bd83-7827a85f78ef
Barisic, Ingeborg
eecca9c6-6878-4b68-9b6c-ff0bbb3057ff
Bianchi, Fabrizio
b064d3bd-f0c0-4177-abf4-9801479be1e9
Garne, Ester
1e675ea0-ae2a-42a4-a851-894b4d1abd58
Nelen, Vera
ededae3e-3112-441c-aac5-6be079546a5b
Neville, Amanda Julie
63fb17ad-d9b7-4b4c-9174-b90bb614c448
Wellesley, Diana
17cbd6c1-0efb-4df1-ae05-64a44987c9c0
Dolk, Helen
cba8a92e-f592-4184-b729-bf852da54e6e
Taruscio, Domenica, Mantovani, Alberto, Carbone, Pietro, Barisic, Ingeborg, Bianchi, Fabrizio, Garne, Ester, Nelen, Vera, Neville, Amanda Julie, Wellesley, Diana and Dolk, Helen
(2015)
Primary prevention of congenital anomalies: recommendable, feasible and achievable.
Public Health Genomics, 18 (3), .
(doi:10.1159/000379739).
Abstract
Primary prevention of congenital anomalies was identified as an important action in the field of rare diseases by the European Commission in 2008, but it was not included in the Council Recommendation on an action in the field of rare diseases in 2009. However, primary prevention of congenital anomalies is feasible because scientific evidence points to several risk factors (e.g., obesity, infectious and toxic agents) and protective factors (e.g., folic acid supplementation and glycemic control in diabetic women). Evidence-based community actions targeting fertile women can be envisaged, such as risk-benefit evaluation protocols on therapies for chronic diseases, vaccination policies, regulations on workplace and environmental exposures as well as the empowerment of women in their lifestyle choices. A primary prevention plan can identify priority targets, exploit and integrate ongoing actions and optimize the use of resources, thus reducing the health burden for the new generation. The EUROCAT-EUROPLAN recommendations for the primary prevention of congenital anomalies endorsed in 2013 by the European Union Committee of Experts on Rare Diseases present an array of feasible and evidence-based measures from which national plans can adopt and implement actions based on country priorities. Primary prevention of congenital anomalies can be achieved here and now and should be an integral part of national plans on rare diseases.
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Accepted/In Press date: 6 February 2015
Published date: June 2015
Organisations:
Human Development & Health
Identifiers
Local EPrints ID: 375438
URI: http://eprints.soton.ac.uk/id/eprint/375438
ISSN: 1662-4246
PURE UUID: 81808dad-2d5f-4aa0-a241-c5e15ecc2849
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Date deposited: 26 Mar 2015 14:03
Last modified: 14 Mar 2024 19:25
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Contributors
Author:
Domenica Taruscio
Author:
Alberto Mantovani
Author:
Pietro Carbone
Author:
Ingeborg Barisic
Author:
Fabrizio Bianchi
Author:
Ester Garne
Author:
Vera Nelen
Author:
Amanda Julie Neville
Author:
Diana Wellesley
Author:
Helen Dolk
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